Nadol'nik L I, Chaĭkovskaia N A, Beluga V B, Vinogradov V V
Ukr Biokhim Zh (1978). 1990 Jul-Aug;62(4):77-80.
Spectral-fluorescent parameters of rat transcortin isolated from blood plasma of intact rats and rats with circulatory insufficiency were studied. The differences in the Schtern Folmer constants and the dissociation constants for the transcortin-corticosterone complex obtained during the protein titration by corticosterone may be due to different tryptophanyl surroundings in the molecules of the studied proteins. This may be a consequence of the conformational rearrangements of the corticosteroid-binding globulin molecules.
对从正常大鼠和循环功能不全大鼠血浆中分离出的大鼠皮质素转运蛋白的光谱荧光参数进行了研究。在用皮质酮对蛋白质进行滴定过程中获得的皮质素转运蛋白 - 皮质酮复合物的施特恩 - 福尔默常数和解离常数的差异，可能是由于所研究蛋白质分子中色氨酸周围环境不同所致。这可能是皮质类固醇结合球蛋白分子构象重排的结果。
