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[鸡胚胎期和胚胎后期脑与肝脏的血流情况]

[Blood flow in the brain and liver of chicken in embryonal and early postembryonal periods].

作者信息

Turganbaeva A S, Belichenko V M, Shoshenko K A

出版信息

Ross Fiziol Zh Im I M Sechenova. 2011 Dec;97(12):1361-72.

PMID:22384677
Abstract

In chicken Leghorn, blood flow volume speed (BF, laser-Doppler flowmetry) in the brain hemispheres and in liver was measured on days 10, 14, and 19 of embryogenesis and on day 4 after hatching (in experiments on late embryos and chickens, urethane narcosis was used). It was revealed, that initial BF in investigated organs was 2-fold lower than earlier measured in skeletal muscles. In the liver, low BF remained at all periods, but it grew 5-fold greater after hatching. In the brain hemispheres, the BF during this period grows gradually reaching 4-fold size in chickens. It was shown that blood stream increase in the brain was accompanied by uniform increase in anatomic lumen of internal carotid artery; thus settlement sizes of linear speed of blood flow and wall shear stress remain in it at the same level. Lumen extension of celiac artery during the observation period lags behind increases in a blood stream of in it that leads to increase in it of the named parameters.

摘要

在来亨鸡胚胎发育的第10天、14天和19天以及孵化后第4天(在晚期胚胎和雏鸡实验中使用了氨基甲酸乙酯麻醉),测量了大脑半球和肝脏的血流体积速度(BF,激光多普勒血流仪测量)。结果显示,所研究器官的初始血流体积速度比之前在骨骼肌中测得的低2倍。在肝脏中,低血流体积速度在所有时期都保持不变,但在孵化后增长了5倍。在大脑半球中,这一时期的血流体积速度逐渐增加,在雏鸡中达到4倍大小。结果表明,大脑中血流增加伴随着颈内动脉解剖管腔的均匀增加;因此,其中血流线性速度和壁面剪应力的稳定大小保持在同一水平。在观察期内,腹腔动脉管腔的扩张落后于其中血流的增加,这导致其中上述参数的增加。

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