Department of Apiculture and Sericulture, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
J Invertebr Pathol. 2012 May;110(1):68-72. doi: 10.1016/j.jip.2012.02.009. Epub 2012 Feb 22.
Propolis is derived from plant resins, collected by honeybees (Apis mellifera) and renown for its antibacterial properties. Here we test the antibacterial effects of ethanolic extracts of propolis from different origins on Paenibacillus larvae, the bacterial pathogen that causes American Foulbrood, a larval disease that can kill the honeybee colony. All tested propolis samples inhibited significantly the growth of P. larvae tested in vitro. The extracts showed major differences in the content of total flavonoids (ranging from 2.4% to 16.4%) and the total polyphenols (ranging between 23.3% and 63.2%). We found that it is not only the content of compounds in propolis, which influences the strength of antimicrobial effects but there is also a significant interaction effect among flavonoids of the propolis extracts. We propose that interaction effects among the various chemical compounds in propolis should be taken into account when considering the antibacterial effects against honeybee pathogens.
蜂胶源于植物树脂，由蜜蜂（Apis mellifera）采集，以其抗菌特性而闻名。在这里，我们测试了来自不同来源的蜂胶乙醇提取物对导致美洲幼虫腐臭病（一种可杀死蜜蜂群体的幼虫病）的蜡螟细菌病原体的抗菌作用。所有测试的蜂胶样本都显著抑制了体外测试的 P. 幼虫的生长。提取物中总类黄酮（2.4％至 16.4％）和总多酚（23.3％至 63.2％）的含量存在很大差异。我们发现，不仅是蜂胶中化合物的含量影响抗菌效果的强度，而且蜂胶提取物中的类黄酮之间还存在显著的相互作用效应。我们提出，在考虑针对蜜蜂病原体的抗菌作用时，应考虑蜂胶中各种化合物之间的相互作用效应。
