Renaud G, Beauge F, Rey C, Infante R
Experientia. 1979 Jun 15;35(6):738-9. doi: 10.1007/BF01968213.
High acetone levels occur in uncontrolled diabetes and after isopropanol administration to rats. In both conditions, very low density lipoproteins (VLDL) secretion is depressed. Acetone, hoever, failed to affect the VLDL secretion rate by the isolated perfused rat liver, suggesting that this metabolite is not involved in impaired VLDL production in diabetes and after isopropanol administration.
丙酮水平升高出现在未得到控制的糖尿病患者以及给大鼠注射异丙醇之后。在这两种情况下，极低密度脂蛋白（VLDL）的分泌都会受到抑制。然而，丙酮对离体灌注的大鼠肝脏的VLDL分泌速率没有影响，这表明这种代谢产物与糖尿病及注射异丙醇后VLDL生成受损无关。
