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帕金森病中的淡漠和快感缺乏

Apathy and anhedonia in Parkinson's disease.

作者信息

Kaji Yoshiaki, Hirata Koichi

机构信息

Department of Neurology, Dokkyo Medical University, 880-Kitakobayashi, Mibu, Tochigi 321-0293, Japan.

出版信息

ISRN Neurol. 2011;2011:219427. doi: 10.5402/2011/219427. Epub 2011 Aug 18.

DOI:10.5402/2011/219427
PMID:22389809
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3263557/
Abstract

Depression, apathy, and anhedonia are often comorbid in patients with Parkinson's disease. Since the morbid states of apathy and anhedonia are complicated, these symptoms are often difficult to diagnose. Several therapeutic methods for apathy and anhedonia are considered effective. However, the validity of these methods has not been established. Similar to depression, apathy and anhedonia clearly affect the quality of life of patients and their families. Therefore, accurate diagnoses of morbid states in the early stage of the disease and corresponding appropriate treatments should be given high priority.

摘要

抑郁症、冷漠和快感缺乏在帕金森病患者中常常并存。由于冷漠和快感缺乏的病态较为复杂,这些症状往往难以诊断。有几种针对冷漠和快感缺乏的治疗方法被认为是有效的。然而,这些方法的有效性尚未得到证实。与抑郁症相似,冷漠和快感缺乏明显影响患者及其家人的生活质量。因此,应高度重视在疾病早期对病态进行准确诊断并给予相应的适当治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa9/3263557/151c83cb7876/NEUROLOGY2011-219427.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa9/3263557/e3368ba0b635/NEUROLOGY2011-219427.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa9/3263557/d95e26cba69d/NEUROLOGY2011-219427.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa9/3263557/b386a3623ce9/NEUROLOGY2011-219427.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa9/3263557/151c83cb7876/NEUROLOGY2011-219427.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa9/3263557/e3368ba0b635/NEUROLOGY2011-219427.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa9/3263557/d95e26cba69d/NEUROLOGY2011-219427.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa9/3263557/b386a3623ce9/NEUROLOGY2011-219427.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa9/3263557/151c83cb7876/NEUROLOGY2011-219427.004.jpg

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本文引用的文献

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Diagnostic criteria for apathy in clinical practice.临床实践中淡漠的诊断标准。
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Pramipexole for the treatment of depressive symptoms in patients with Parkinson's disease: a randomised, double-blind, placebo-controlled trial.普拉克索治疗帕金森病患者抑郁症状的随机、双盲、安慰剂对照试验。
罗马尼亚队列中选定帕金森病患者 3 年死亡率的危险因素。
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Depressive Symptoms and Their Impact on Quality of Life in Parkinson's Disease: An Exploratory Network Analysis Approach.帕金森病中的抑郁症状及其对生活质量的影响:一种探索性网络分析方法
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Management of Psychiatric Disorders in Patients with Parkinson's Diseases.帕金森病患者精神障碍的管理
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Apathy and Anhedonia: Clinical and Neurophysiological Assessment of a Romanian Cohort.冷漠与快感缺乏:罗马尼亚队列的临床与神经生理学评估
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Insula and Amygdala Atrophy Are Associated With Functional Impairment in Subjects With Presbycusis.脑岛和杏仁核萎缩与老年性聋患者的功能损害有关。
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Heliyon. 2019 Apr 9;5(4):e01481. doi: 10.1016/j.heliyon.2019.e01481. eCollection 2019 Apr.
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