Ozdemir Halil, Candir Mehmet Onur, Karbuz Adem, Belet Nurşen, Tapisiz Anil, Ciftçi Ergin, Ince Erdal
Department of Pediatric Infectious Diseases, Ankara University Faculty of Medicine, Ankara, Turkey.
Turk J Pediatr. 2011 Nov-Dec;53(6):614-25.
The aim of this study was to determine the complications, financial burden and mortality caused by chickenpox using the data of Ankara, Turkey in the pre-vaccination period. The study was conducted as a retrospective sectional study. Of the 65 patients admitted to our hospital, 34 (52.3%) had been previously healthy, 10 (15.4%) had previous chronic disease and 21 (32.3%) were immunocompromised. The most common complications of chickenpox in those patient groups were skin and soft tissue infections (41.2%), hematological complications (50%) and gastrointestinal complications (38.1%), respectively. We found 10.6/100,000 and 8.7/100,000 rates of hospitalization due to chickenpox in Ankara for all children and for previously healthy children, respectively. The chickenpox-related mortality rate for the 0-17 age group was 3.03/1,000,000 in Ankara. In conclusion, we feel that a national vaccination program for chickenpox will lead to a significant decrease in the overall cost to our country.
本研究旨在利用土耳其安卡拉疫苗接种前时期的数据，确定水痘所致的并发症、经济负担和死亡率。该研究作为一项回顾性横断面研究开展。在我院收治的65例患者中，34例（52.3%）此前身体健康，10例（15.4%）有既往慢性病，21例（32.3%）存在免疫功能低下。在这些患者群体中，水痘最常见的并发症分别为皮肤和软组织感染（41.2%）、血液学并发症（50%）和胃肠道并发症（38.1%）。我们发现，安卡拉所有儿童和既往健康儿童因水痘住院的比例分别为10.6/10万和8.7/10万。安卡拉0 - 17岁年龄组的水痘相关死亡率为3.03/100万。总之，我们认为全国性的水痘疫苗接种计划将使我国的总体成本大幅降低。
