Institute of Fermentation Technology and Microbiology, Technical University of Łódź, Poland.
Pol J Microbiol. 2011;60(4):329-33.
Gut microbiota was analyzed in children, aged 6-18 months and suffering from atopic dermatitis before and after 3 month supplementation of their diet with Lactobacillus casei DN--114001 in a dose of 109 cells daily. On completion of this period the total number of fecal Lactobacillus sp. cells decreased from 7.86 Log10 CFU/g to 6.40 Log10 CFU/g. After the next 5 months (without dietary supplementation with the probiotic bacteria) the level of Lactobacillus sp. cells was maintained at the latter value. During the dietary supplementation with the probiotic strain, the level of Bifidobacterium cells was maintained at 6.15-6.89 Log10 CFU/g while after 5 months it decreased to 5.57 Log10 CFU/g. The population of Clostridium sp. was reduced after 3 months of dietary supplementation from 6.49 to 5.83 Log10 CFU/g and was maintained at the latter level during the next 5 months. The dietary supplementation had no effect on populations of Bacteroides sp., Enterococcus sp. and Enterobacteriaceae. Supplementation of children who developed atopic dermatitis with the preparation of Lactobacillus casei DN - 114001 positively affected their gut microbiota in terms of bifidobacteria and clostridia populations.
在补充剂量为 10^9 细胞/天的干酪乳杆菌 DN-114001 3 个月后，对患有特应性皮炎的 6-18 个月大的儿童进行了肠道微生物群分析。在这段时间结束时，粪便乳杆菌属细胞的总数从 7.86 Log10 CFU/g 减少到 6.40 Log10 CFU/g。在接下来的 5 个月（没有用益生菌进行饮食补充）中，乳杆菌属细胞的水平保持在后者的值。在补充益生菌株期间，双歧杆菌细胞的水平保持在 6.15-6.89 Log10 CFU/g，而 5 个月后下降到 5.57 Log10 CFU/g。在补充饮食 3 个月后，梭菌属的数量从 6.49 减少到 5.83 Log10 CFU/g，在接下来的 5 个月中保持在后者的水平。饮食补充对拟杆菌属、肠球菌属和肠杆菌科的数量没有影响。在补充干酪乳杆菌 DN-114001 后，患有特应性皮炎的儿童的肠道微生物群中双歧杆菌和梭菌属的数量增加。
