Department of Nuclear Medicine, Geneva University Medical Center, Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Clin Nucl Med. 2012 Apr;37(4):339-43. doi: 10.1097/RLU.0b013e318239248b.
SPECT fused with computed tomography (CT) provides a new approach for more accurate diagnosis of pseudathrosis after spinal fusion procedures. The aim of this study was to compare the findings of SPECT fused with CT (SPECT/CT) with those of CT alone for the diagnosis of pseudarthrosis.
SPECT and CT of 10 consecutive patients with recurrence of back and/or leg pain and with suspicion of pseudarthrosis on conventional radiologic imaging were analyzed retrospectively. All had previously undergone anterior and/or posterior lumbar fusion techniques. Presence of screw loosening, nonunion through or around the cages, and facet joint degeneration were assessed for diagnosis of pseudarthrosis. Based on SPECT/CT scan findings, the decision of surgical reintervention was made on 6 of 10 patients. The clinical follow-up (mean, 15.6 months; range, 5-29 months) was evaluated according to Macnab criteria (excellent, good, fair, poor).
All patients showing screw loosening on CT alone showed also an abnormal uptake on SPECT/CT. SPECT/CT did not show abnormal uptake in 3 of 5 patients who had nonunion through/around the cages on CT alone. SPECT/CT was able to show increased uptake in 6 cases in which CT alone did not show facet joint degeneration.
In the lumbar spine, SPECT/CT seems to increase specificity for detection of nonunion of interbody devices compared with CT alone. It is more sensitive than CT to detect facet joint degeneration, and it can detect screw loosening as well as CT. These findings can be helpful for surgeons in planning appropriate surgical revision strategy.
SPECT 融合计算机断层扫描(CT)为脊柱融合术后假关节的更准确诊断提供了一种新方法。本研究旨在比较 SPECT 融合 CT(SPECT/CT)与单独 CT 对假关节的诊断结果。
回顾性分析 10 例连续出现腰背疼痛和/或下肢疼痛且常规影像学检查怀疑假关节的患者的 SPECT 和 CT 检查资料。所有患者均行前路和/或后路腰椎融合术。评估螺钉松动、笼内或周围骨不连以及小关节退变的情况,以诊断假关节。根据 SPECT/CT 扫描结果,对 10 例患者中的 6 例决定行再次手术干预。根据 Macnab 标准(优、良、可、差)对临床随访(平均 15.6 个月;范围 5-29 个月)进行评估。
所有单独 CT 显示螺钉松动的患者在 SPECT/CT 上也显示异常摄取。单独 CT 显示 5 例笼内或周围骨不连的患者中,有 3 例 SPECT/CT 未见异常摄取。SPECT/CT 能够显示出 6 例单独 CT 未显示小关节退变的病例中摄取增加。
在腰椎中,SPECT/CT 似乎比单独 CT 更能提高对椎间融合器不连的检测特异性。它比 CT 更能敏感地检测小关节退变,并且可以像 CT 一样检测螺钉松动。这些发现可以帮助外科医生制定适当的手术修正策略。