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苏丹某教学医院术后患者医院获得性伤口感染的患病率及抗生素使用模式

Prevalence of nosocomial wound infection among postoperative patients and antibiotics patterns at teaching hospital in Sudan.

作者信息

Ahmed Mohamed Issa

机构信息

Department of Medical Laboratories, College of Applied Medical Science, Qassim University, Saudi Arabia.

出版信息

N Am J Med Sci. 2012 Jan;4(1):29-34. doi: 10.4103/1947-2714.92900.

Abstract

BACKGROUND

Postoperative nosocomial infections remain a major problem in health care facilities, resulting in extended length of stay, substantial morbidity and mortality, high excess of cost, and less frequent cause of death in the surgical patient.

AIMS

To determine the prevalence of aerobic nosocomial pathogens among patients with postoperative wound infections at Gadarif state which located in Eastern part of Sudan.

MATERIALS AND METHODS

109 wound swabs were collected from patients who had developed postoperative wound infection. Conventional technique for isolation of bacteria was applied with analytical profile index (API system) for identification to confirm primary and secondary isolates. Antibiotics susceptibility was applied for all isolated bacteria.

RESULTS

Aerobic bacterial isolates were S. aureus (n=55, 55.0%), P. mirabilis (n=35, 35.0%), E. coli (n=5, 5.0%), Ps. aeruginosa (n=3, 3.0%), and Pr. vulgaris (n=2, 2.0%). The prevalence rate of hospital acquired infection were 25.23%

CONCLUSION

The highest prevalence rate of nosocomial postoperative wound infection, in Sudan was due to poor antibiotic selection, for prophylaxis during and after surgery and increased level of contamination in most part of the hospital.

摘要

背景

术后医院感染仍是医疗机构中的一个主要问题,导致住院时间延长、大量发病和死亡、成本大幅超支,并且是外科患者中较不常见的死亡原因。

目的

确定位于苏丹东部加达里夫州的术后伤口感染患者中需氧医院病原体的患病率。

材料与方法

从发生术后伤口感染的患者中收集109份伤口拭子。采用常规细菌分离技术,并使用分析谱指数(API系统)进行鉴定,以确认主要和次要分离株。对所有分离出的细菌进行抗生素敏感性检测。

结果

需氧菌分离株为金黄色葡萄球菌(n = 55,55.0%)、奇异变形杆菌(n = 35,35.0%)、大肠杆菌(n = 5,5.0%)、铜绿假单胞菌(n = 3,3.0%)和普通变形杆菌(n = 2,2.0%)。医院获得性感染的患病率为25.23%。

结论

在苏丹,术后伤口医院感染的患病率最高是由于抗生素选择不当、手术期间和术后预防措施不足以及医院大部分区域污染水平增加。

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