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约旦北部公立医院外科手术部位感染分离出的病原菌的抗生素谱

Antibiotic Profile of Pathogenic Bacteria Isolated from Postsurgical Site Infections in Public Hospitals in Northern Jordan.

作者信息

Ennab Raed, Al-Momani Waleed, Al-Titi Rama, Elayan Ayah

机构信息

Department of Clinical Medical Sciences/General Surgery, Faculty of Medicine, Yarmouk University, Irbid, Jordan.

Department of Basic Medical Sciences/Microbiology, Faculty of Medicine, Yarmouk University, Irbid, Jordan.

出版信息

Infect Drug Resist. 2022 Feb 2;15:359-366. doi: 10.2147/IDR.S350406. eCollection 2022.

Abstract

BACKGROUND

Surgical site infections are hospital-acquired, vary from one hospital to another, and can cause significant postoperative morbidity, mortality, and prolonged hospital stay.

OBJECTIVE

The main aim of the study was to identify the bacterial pathogens associated with surgical site infections and their antibiotic susceptibility in a public hospital in northern Jordan.

METHODS

Postsurgical wound samples were collected and processed in a microbiology laboratory using standard microbiological techniques. Antibiotic susceptibility tests were performed using 13 antibiotics covering the gram-positive and gram-negative bacteria using the disc diffusion test.

RESULTS

The bacterial species that were identified in this study include 8 (29%), 3 (11%), 1 (3.5%), 4 (14%), 2 (7%), 8 (29%), 1 (3.5%), and 1 (4%). The antibiotic profiles of these bacteria showed high resistance. The MAR indices showed that 17 of 28 bacteria isolated were above 0.2 indicating high resistance.

CONCLUSION

Resistant bacteria are becoming more dominant in wound infections with a high prevalence of multidrug resistant isolates. Hospital disinfection and treatment protocols regarding the use of antibiotics should be practiced vigorously and monitored regularly to combat resistance.

摘要

背景

手术部位感染是医院获得性感染,因医院而异,可导致显著的术后发病率、死亡率和住院时间延长。

目的

本研究的主要目的是确定约旦北部一家公立医院中与手术部位感染相关的细菌病原体及其抗生素敏感性。

方法

收集术后伤口样本,并在微生物实验室使用标准微生物技术进行处理。使用纸片扩散法,对覆盖革兰氏阳性菌和革兰氏阴性菌的13种抗生素进行抗生素敏感性试验。

结果

本研究中鉴定出的细菌种类包括8种(29%)、3种(11%)、1种(3.5%)、4种(14%)、2种(7%)、8种(29%)、1种(3.5%)和1种(4%)。这些细菌的抗生素谱显示出高耐药性。多重耐药指数显示,分离出的28种细菌中有17种高于0.2,表明耐药性高。

结论

耐药菌在伤口感染中变得更加占主导地位,多重耐药菌株的患病率很高。应大力实施并定期监测医院关于抗生素使用的消毒和治疗方案,以对抗耐药性。

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