Huang Ping, Li Shi-Ying, Li Zheng-Dong, Shao Yu, Li Li, Chen Yuan-Yuan, Chen Yi-Jiu
Shanghai Key Laboratory of Forensic Medicine, Institute of Forensic Science, Ministry of Justice, Shanghai 200063, PR China.
Fa Yi Xue Za Zhi. 2011 Dec;27(6):447-50.
Fourier transformation infrared microspectroscopy (FTIR-MSP) mapping technique can collect the infrared information from micro-samples and scan the tissue slides and cells. The infrared spectral information of pixels from the collected regions is recorded and infrared spectral maps are constructed by computer software. The 2D and 3D mapping images are reflected based on the distributions of absorbance bands. The biochemical compositions, molecular distribution, metabolic changes of tissues and cells are analyzed by the technique due to infrared spectroscopy being sensitive to biomolecules. The article reviews the recent research of FTIR-MSP mapping and explores the future potential value in forensic science practice.
傅里叶变换红外显微光谱（FTIR-MSP）映射技术可以从微量样本中收集红外信息，并扫描组织切片和细胞。记录所采集区域像素的红外光谱信息，并通过计算机软件构建红外光谱图。基于吸收带的分布反映二维和三维映射图像。由于红外光谱对生物分子敏感，该技术可用于分析组织和细胞的生化组成、分子分布及代谢变化。本文综述了FTIR-MSP映射的最新研究，并探讨了其在法医学实践中的未来潜在价值。
