Şıklar Zeynep, Berberoğlu Merih, Yağmurlu Aydın, Hacıhamdioğlu Bülent, Savaş Erdeve Senay, Fitöz Suat, Kır Metin, Öçal Gönül
Ankara University Faculty of Medicine, Department of Pediatrics Endocrinology, Ankara, Turkey.
J Clin Res Pediatr Endocrinol. 2012 Mar;4(1):30-3. doi: 10.4274/jcrpe.477.
Thyroid carcinoma (TC) combined with congenital hypothyroidism is rare. The synchronous occurrence of these two conditions is even rarer. We describe a patient with congenital hypothyroidism in whom hyperthyroglobulinemia and nodules developed despite adequate replacement therapy. Papillary TC was detected at age 19 years. Postoperative diagnostic scintigraphy showed increased uptake in the thyroglossal duct region. Repetitive imaging of the thyroid gland can be useful in the early detection of TC in patients with congenital hypothyroidism. Moreover, this rare situation can be complicated by a synchronous thyroglossal duct carcinoma. Thyroglossal duct carcinoma can be detected if diagnostic scintigraphy is performed after total thyroidectomy.
甲状腺癌（TC）合并先天性甲状腺功能减退症很罕见。这两种情况同时出现则更为罕见。我们描述了一名患有先天性甲状腺功能减退症的患者，尽管进行了充分的替代治疗，但仍出现了甲状腺球蛋白血症和结节。该患者19岁时被检测出乳头状甲状腺癌。术后诊断性闪烁扫描显示甲状舌管区域摄取增加。对先天性甲状腺功能减退症患者进行甲状腺重复成像有助于早期发现甲状腺癌。此外，这种罕见情况可能并发同步性甲状舌管癌。全甲状腺切除术后进行诊断性闪烁扫描可检测出甲状舌管癌。
