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通过对近红外光谱信号的自适应滤波进行皮质脑成像。

Cortical brain imaging by adaptive filtering of NIRS signals.

机构信息

Department of Cogno-Mechatronics Engineering, Pusan National University, 30 Jangjeon-dong, Geumjeong-gu, Busan 609-735, Republic of Korea.

出版信息

Neurosci Lett. 2012 Apr 11;514(1):35-41. doi: 10.1016/j.neulet.2012.02.048. Epub 2012 Feb 25.

DOI:10.1016/j.neulet.2012.02.048
PMID:22395086
Abstract

This paper presents an online brain imaging framework for cognitive tasks conducted with functional near-infrared spectroscopy (fNIRS). The measured signal at each channel is regarded as the output from a linear system with unknown coefficients. The unknown coefficients are estimated by using the recursive least squares estimation (RLSE) method. The validity of the estimated parameters is tested using the t-statistics. Contrary to the classical approach that is offline and applies the same preprocessing scheme to all channels, the proposed RLSE method for a linear model formulation provides an independent robust adaptive process for individual channels. The experiments carried out with two fNIRS instruments (continuous-wave and frequency-domain) have verified the potential of the proposed methodology which can facilitate a prompt medical diagnostics by providing real-time brain activation maps.

摘要

本文提出了一种基于功能近红外光谱 (fNIRS) 的在线脑成像框架,用于认知任务。每个通道的测量信号被视为具有未知系数的线性系统的输出。未知系数通过使用递归最小二乘估计 (RLSE) 方法进行估计。通过 t 统计量检验估计参数的有效性。与经典方法不同,经典方法是离线的,对所有通道应用相同的预处理方案,用于线性模型公式的 RLSE 方法为每个通道提供了独立的稳健自适应过程。使用两种 fNIRS 仪器 (连续波和频域) 进行的实验验证了该方法的潜力,该方法可以通过提供实时脑激活图来促进快速的医学诊断。

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