Department of Epidemiology and Population Studies, Institute of Public Health, Faculty of Health Sciences, Jagiellonian University Medical College, Kraków, Poland.
Eur J Prev Cardiol. 2013 Apr;20(2):331-40. doi: 10.1177/2047487312441724. Epub 2012 Mar 6.
To assess in coronary heart disease (CHD) patients: (1) differences in the prevalence of depression and anxiety between samples selected from 22 countries; (2) the association of depression and anxiety with age, education, diagnostic category, favourable behaviours, use of cardioprotective drugs, and reaching the secondary prevention treatment targets.
Cross-sectional study.
The study group consisted of 8580 patients from 22 European countries examined at least 6 months after hospitalization due to CHD. Depression and anxiety were assessed using Hospital Anxiety and Depression Scale (HADS).
Prevalence of depression (HADS depression score ≥ 8) varied from 8.2% to 35.7% in men and from 10.3% to 62.5% in women. Prevalence of anxiety (HADS anxiety score ≥ 8) varied from 12.0% to 41.8% in men and from 21.5% to 63.7% in women. Older age, female sex, low education, and no history of invasive treatment were associated with more frequent depression and anxiety. Depression and anxiety were associated with less frequent modification of lifestyle. Depression was related with body mass index, waist circumference, fasting glucose, and more frequent self-reported diabetes but not with reaching the treatment targets for blood pressure and lipids.
High prevalence of depression and anxiety in CHD patients, and relation with less frequent lifestyle modification, call to integrate methods of identification and minimizing unfavourable effects of depression and anxiety into the cardiac rehabilitation and prevention programmes.
评估冠心病（CHD）患者中：（1）来自 22 个国家的样本中抑郁和焦虑的患病率差异；（2）抑郁和焦虑与年龄、教育程度、诊断类别、有利行为、使用心脏保护药物以及达到二级预防治疗目标的关系。
横断面研究。
研究组由来自 22 个欧洲国家的 8580 例患者组成，这些患者在因 CHD 住院至少 6 个月后接受了检查。使用医院焦虑和抑郁量表（HADS）评估抑郁和焦虑。
男性的抑郁患病率（HADS 抑郁评分≥8）从 8.2%到 35.7%不等，女性从 10.3%到 62.5%不等。男性的焦虑患病率（HADS 焦虑评分≥8）从 12.0%到 41.8%不等，女性从 21.5%到 63.7%不等。年龄较大、女性、教育程度较低、无侵入性治疗史与更频繁的抑郁和焦虑相关。抑郁和焦虑与生活方式改变的频率较低有关。抑郁与体重指数、腰围、空腹血糖和更频繁的自我报告糖尿病有关，但与血压和血脂治疗目标的达标无关。
CHD 患者中抑郁和焦虑的高患病率，以及与生活方式改变频率较低有关，呼吁将识别和减轻抑郁和焦虑不良影响的方法纳入心脏康复和预防计划。
