Bhargava V, Sunnerhagen K S, Rashwan M, Podolin R A, Shabetai R
University of California, San Diego.
Am Heart J. 1990 Nov;120(5):1058-72. doi: 10.1016/0002-8703(90)90117-g.
Eighty patients with ischemic heart disease and 17 normal subjects were evaluated for left ventricular regional wall motion by means of a new method. The wall motion analysis is based on video intensity. This technique uses a temporally sliding analysis to evaluate the cardiac cycle in 100 msec intervals. Presence of coronary artery disease was defined as more than 50% measured diameter stenosis. Wall motion abnormalities in regions perfused by stenotic vessels were most common in early diastole (76%). Sensitivity of this method at rest in patients with coronary artery disease was 79.7% (p less than 0.0001) and overall accuracy was 84.2% (p less than 0.0001). Abnormalities in both systole and diastole were more common in regions perfused by severe lesions (greater than 75%) than in those perfused by moderately stenotic (less than 75%) vessels (p less than 0.05). A comparison of the new method with phase and amplitude analysis was performed in 15 patients and with two-frame analysis in 40 patients. This new method yielded a higher sensitivity than either of the other two methods.
采用一种新方法对80例缺血性心脏病患者和17例正常受试者的左心室局部壁运动进行了评估。壁运动分析基于视频强度。该技术采用时间滑动分析，以100毫秒的间隔评估心动周期。冠状动脉疾病的定义为测量的直径狭窄超过50%。狭窄血管灌注区域的壁运动异常在舒张早期最为常见（76%）。该方法在冠状动脉疾病患者静息状态下的敏感性为79.7%（p<0.0001），总体准确率为84.2%（p<0.0001）。严重病变（大于75%）灌注区域的收缩期和舒张期异常比中度狭窄（小于75%）血管灌注区域更常见（p<0.05）。对15例患者进行了该新方法与相位和幅度分析的比较，对40例患者进行了该新方法与双帧分析的比较。该新方法的敏感性高于其他两种方法中的任何一种。
