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巴西全国多中心研究:日常临床实践中达到治疗目标的 1 型糖尿病成人患者的患病率。

Prevalence of adults with type 1 diabetes who meet the goals of care in daily clinical practice: a nationwide multicenter study in Brazil.

机构信息

Department of Internal Medicine, Diabetes Unit, State University Hospital of Rio de Janeiro, Brazil.

出版信息

Diabetes Res Clin Pract. 2012 Jul;97(1):63-70. doi: 10.1016/j.diabres.2012.02.008. Epub 2012 Mar 6.

Abstract

OBJECTIVE

To determine the prevalence of patients with type 1 diabetes mellitus who meet the glycemic and cardiovascular (CV) risk factors goals and the frequency of screening for diabetic complications in Brazil according to the American Diabetes Association guidelines.

RESEARCH DESIGN AND METHODS

This was a cross-sectional, multicenter study conducted between December 2008 and December 2010 in 28 public clinics in 20 Brazilian cities. Data were obtained from 1774 adult patients (56.8% females, 57.2% Caucasians) aged 30.3 ± 9.8 years with diabetes duration of 14.3 ± 8.8 years.

RESULTS

Systolic blood pressure was at goal in 40.3% and diastolic blood pressure was at goal in 26.6% of hypertensive patients. LDL cholesterol and HbA1c were at the goal in 45.2% and 13.2% of the patients, respectively. Overweight was presented in 25.6% and obesity in 6.9%. Among those with more than 5 years of disease, screening for retinopathy was performed in the preceding year in 70.1%. Nephropathy and feet complications were screened in 63.1% and 65.1%, respectively.

CONCLUSIONS

The majority of patients did not meet metabolic control goals and a substantial proportion was not screened for diabetic complications. These issues may increase the risk of chronic complications and negatively impact public health.

摘要

目的

根据美国糖尿病协会的指南,确定符合血糖和心血管(CV)危险因素目标的 1 型糖尿病患者的患病率,以及在巴西筛查糖尿病并发症的频率。

研究设计和方法

这是一项横断面、多中心研究,于 2008 年 12 月至 2010 年 12 月在巴西 20 个城市的 28 个公共诊所进行。研究数据来自 1774 名成年患者(56.8%为女性,57.2%为白种人),年龄 30.3±9.8 岁,糖尿病病程 14.3±8.8 年。

结果

高血压患者中,40.3%的收缩压达标,26.6%的舒张压达标。45.2%的患者 LDL 胆固醇和 13.2%的患者 HbA1c 达标。25.6%的患者超重,6.9%的患者肥胖。在病程超过 5 年的患者中,有 70.1%的患者在前一年进行了视网膜病变筛查。分别有 63.1%和 65.1%的患者进行了肾病和足部并发症筛查。

结论

大多数患者未达到代谢控制目标,相当一部分患者未进行糖尿病并发症筛查。这些问题可能会增加慢性并发症的风险,对公共卫生产生负面影响。

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