VanItallie T B, Yang M U, Heymsfield S B, Funk R C, Boileau R A
Department of Medicine, College of Physicians and Surgeons, Columbia University St Luke's-Roosevelt Hospital Center, New York, NY 10025.
Am J Clin Nutr. 1990 Dec;52(6):953-9. doi: 10.1093/ajcn/52.6.953.
Expressing fat-free mass (FFM) and body fat mass (BFM) as percentages of body weight or by weight is unsatisfactory. For example, tall patients with protein-energy malnutrition (PEM) can exhibit values for FFM and BFM similar to those of shorter well-nourished individuals. To obviate such difficulties, we propose use of height-normalized indices, namely, a FFM index [FFM (kg)/height (m)2, or FFMI] and a BFM index [BFM (kg)/height (m)2, or BFMI]. We calculated these indices in a reference population of 124 healthy young men and in 32 nonobese young men (from the Minnesota Study) before, during, and after experimental semistarvation. When values for FFMI and BFMI falling below the reference cohort's 5th percentile cutoff point were used as a criterion for PEM, these indices, together with basal oxygen-consumption rate, diagnosed PEM in 27 of the 32 Minnesota Study subjects after 12 wk of semi-starvation. These findings indicate that FFMI and BFMI may be useful in nutritional assessment.
将去脂体重（FFM）和体脂肪量（BFM）表示为体重的百分比或按体重计算并不理想。例如，患有蛋白质 - 能量营养不良（PEM）的高个子患者的FFM和BFM值可能与身材较矮但营养良好的个体相似。为了避免此类困难，我们建议使用身高标准化指数，即FFM指数[FFM（千克）/身高（米）²，或FFMI]和BFM指数[BFM（千克）/身高（米）²，或BFMI]。我们在124名健康年轻男性的参考人群以及32名非肥胖年轻男性（来自明尼苏达研究）中，在实验性半饥饿前、期间和之后计算了这些指数。当将低于参考队列第5百分位数切点的FFMI和BFMI值用作PEM的标准时，在半饥饿12周后，这些指数与基础氧消耗率一起，在32名明尼苏达研究对象中的27名中诊断出PEM。这些发现表明，FFMI和BFMI可能在营养评估中有用。
