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患有前列腺腺癌的年轻黑人存活率降低。

Diminished survival of young blacks with adenocarcinoma of the prostate.

作者信息

Austin J P, Aziz H, Potters L, Thelmo W, Chen P, Choi K, Brandys M, Macchia R J, Rotman M

机构信息

Department of Radiation Oncology, State University of New York Health Science Center, Brooklyn 11203.

出版信息

Am J Clin Oncol. 1990 Dec;13(6):465-9. doi: 10.1097/00000421-199012000-00002.

Abstract

The survival rates of 117 black and white patients treated by primary radiation for carcinoma of the prostate at the State University of New York Health Science Center at Brooklyn and Kings County Hospital Center were analyzed according to age and race. In addition, stage, grade, and delay time in seeking medical attention were analyzed. Survival was similar in both young (less than 60 years) and old (greater than or equal to 60 years) patients, with 45% and 41% 5-year-survival rates, respectively. Survival was better in white patients, 48% 5-year survival, than in blacks, 35% 5-year survival. Black patients presented with higher stage disease than whites (p less than 0.01). This trend was even greater in young black males, who had higher grade (64% versus 11%; p less than 0.04) and higher stage tumors (p less than 0.05). In addition, young blacks delayed seeking medical attention greater than 3 months 72% of the time, as compared to 0% in white young males (p less than 0.005). A survival difference was also seen in young blacks as compared with young whites: 3.9-year median survival versus 6.0-year median survival, respectively.

摘要

对纽约州立大学布鲁克林健康科学中心和国王郡医院中心采用原发性放射治疗前列腺癌的117名黑人和白人患者的生存率,按照年龄和种族进行了分析。此外,还分析了疾病分期、分级以及就医延迟时间。年轻(小于60岁)患者和老年(大于或等于60岁)患者的生存率相似,5年生存率分别为45%和41%。白人患者的生存率更高,5年生存率为48%,而黑人患者为35%。黑人患者的疾病分期高于白人(p<0.01)。这种趋势在年轻黑人男性中更为明显,他们的肿瘤分级更高(64%对11%;p<0.04),分期也更高(p<0.05)。此外,72%的年轻黑人就医延迟超过3个月,而白人年轻男性这一比例为0%(p<0.005)。与年轻白人相比,年轻黑人的生存率也存在差异:中位生存期分别为3.9年和6.0年。

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