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前列腺癌生存种族差异的相关因素。

Factors associated with racial differences in survival for prostatic carcinoma.

作者信息

Dayal H H, Chiu C

出版信息

J Chronic Dis. 1982;35(7):553-60. doi: 10.1016/0021-9681(82)90074-1.

DOI:10.1016/0021-9681(82)90074-1
PMID:7085847
Abstract

The survival data on 99 white and 292 black patients with a carcinoma of the prostate from the city of Richmond seem at the Medical College of Virginia between 1968 and 1977 were analyzed. Black patients with prostatic cancer have significantly poorer survival prognosis than whites. The distribution of stage at diagnosis is unfavorable to blacks in comparison to whites. Also, blacks present with less differentiated tumors. Degree of differentiation and clinical stage are highly associated and both are important predictors of survival. The prognosis differential between the two races does not seem to be due to difference in the biology of the disease; it is more likely due to the 'environment', defined in the broadest sense. Socio-economic status is associated with race and explains the racial difference in survival.

摘要

对1968年至1977年间弗吉尼亚医学院收治的里士满市99名白人前列腺癌患者和292名黑人前列腺癌患者的生存数据进行了分析。患有前列腺癌的黑人患者的生存预后明显比白人差。与白人相比,黑人患者确诊时的分期分布对其不利。此外,黑人患者的肿瘤分化程度较低。分化程度和临床分期高度相关,且二者均为生存的重要预测指标。两个种族之间的预后差异似乎并非由于疾病生物学特性的不同;更有可能是由于最广义定义的“环境”因素。社会经济地位与种族相关,并解释了生存方面的种族差异。

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