英夫利昔单抗治疗溃疡性结肠炎并发皮肤结节病。
Cutaneous sarcoidosis in a patient with ulcerative colitis on infliximab.
机构信息
Department of Gastroenterology, Campbelltown Hospital, NSW, Australia University of Western Sydney, NSW, Australia.
出版信息
J Crohns Colitis. 2012 Jul;6(6):708-12. doi: 10.1016/j.crohns.2012.01.008. Epub 2012 Jan 29.
The advance of anti-tumour necrosis factor (TNF) therapy had dramatically changed the treatment algorithm of inflammatory bowel disease (IBD). This had significantly improved the quality of life for patients with Crohn's disease (CD) and ulcerative colitis (UC).(1) However, side-effects of anti-TNF treatment were unavoidable with paradoxical inflammation (for example leucocytoclastic vasculitis and psoriasis) being well-known phenomena of anti-TNF therapy.(2) We report a case of infliximab induced cutaneous sarcoidosis in a patient with ulcerative colitis and review the literature.
抗肿瘤坏死因子（TNF）治疗的进展极大地改变了炎症性肠病（IBD）的治疗方案。这显著提高了克罗恩病（CD）和溃疡性结肠炎（UC）患者的生活质量。(1) 然而，抗 TNF 治疗的副作用是不可避免的，如反常性炎症（如白细胞碎裂性血管炎和银屑病）是抗 TNF 治疗的已知现象。(2) 我们报告了一例溃疡性结肠炎患者使用英夫利昔单抗引起的皮肤类肉瘤病，并复习了文献。
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