Regional Laboratory of Virology, National Reference Laboratory of Gastroenteric Viruses, ÁNTSZ Regional Institute of State Public Health Service, Pécs, Hungary.
Arch Virol. 2012 Jun;157(6):1143-7. doi: 10.1007/s00705-012-1272-4. Epub 2012 Mar 8.
The family Astroviridae consists of two genera, Avastrovirus and Mamastrovirus whose members are associated with gastroenteritis in avian and mammalian hosts, respectively. In this study, we report the first detection of astrovirus from fecal specimens of wild boars (Sus scrofa) using viral metagenomics and complete genome sequencing. The wild boar astrovirus (WBAstV-1/2011/HUN, JQ340310) genome is 6707 nucleotide long and had 76%, 95% and 56% amino acid (aa) identity in the ORF1a (852aa), ORF1b (522aa) and ORF2 (845aa) regions, respectively, to porcine astrovirus 4 (PAstV-4, JF713713), the closest match. This study indicates that wild boar could be a reservoir for astroviruses.
星状病毒科包含两个属，即禽星状病毒属和哺乳动物星状病毒属，其成员分别与禽类和哺乳动物的胃肠炎有关。在本研究中，我们通过病毒宏基因组学和全基因组测序，首次从野猪（Sus scrofa）粪便标本中检测到星状病毒。野猪星状病毒（WBAstV-1/2011/HUN，JQ340310）基因组全长 6707 个核苷酸，其 ORF1a（852 个氨基酸）、ORF1b（522 个氨基酸）和 ORF2（845 个氨基酸）区域与猪星状病毒 4（PAstV-4，JF713713）的同源性分别为 76%、95%和 56%，PAstV-4 是最接近的同源病毒。本研究表明，野猪可能是星状病毒的贮存宿主。
