社交行为的神经生物学。
Neurobiology of sociability.
机构信息
Laboratory of Neuroendocrinology and Behavior, Department of Biological Sciences and School of Biomedical Sciences, Kent State University, Ohio, USA.
出版信息
Adv Exp Med Biol. 2012;739:187-205. doi: 10.1007/978-1-4614-1704-0_12.
Abstract
Sociability consists of behaviors that bring animals together and those that keep animals apart. Remarkably, while the neural circuitry that regulates these two "faces" of sociability differ from one another, two neurohormones, oxytocin (Oxt) and vasopressin (Avp), have been consistently implicated in the regulation of both. In this chapter the the structure and function of the Oxt and Avp systems, the ways in which affiliative and aggressive behavior are studied and the roles of Oxt and Avp in the regulation of sociability will be briefly reviewed. Finally, work implicating Oxt and Avp in sociability in humans, with a focus on neuropsychiatric disorders will be highlighted.
摘要
社交行为由使动物聚集在一起的行为和使动物分开的行为组成。值得注意的是，尽管调节这两种“社交行为”的神经回路彼此不同，但两种神经激素——催产素（Oxt）和加压素（Avp）——一直被认为与两者的调节有关。在这一章中，将简要回顾 Oxt 和 Avp 系统的结构和功能、研究亲和行为和攻击行为的方法以及 Oxt 和 Avp 在调节社交行为中的作用。最后，将重点介绍涉及人类社交行为的 Oxt 和 Avp 的工作，以及神经精神疾病。
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