Comstedt Lisbeth Rosholm, Svensson Ake, Troilius Agneta
Department of Dermatology and Venerology, University Hospital of Skåne, Malmö, Sweden.
J Cosmet Laser Ther. 2012 Apr;14(2):102-6. doi: 10.3109/14764172.2012.672744.
Intense pulsed light (IPL) treatment is well known for, for example, photo rejuvenation, where higher cut-off filters are used. The longer wavelengths penetrate deeper in the dermis leading to damage of the collagen and stimulation of new collagen formation, which lead to more soft and elastic skin. Microstomia in systemic sclerosis is the end result of excessive collagen deposition, which makes the perioral skin firm and tight. The patients have difficulties performing oral self-care, and even professional dental care can be complicated.
Four patients with systemic sclerosis and microstomia were treated with IPL (Ellipse A/S Flex System, Denmark ) in the perioral region. The patients received 3-5 treatments with 4-week interval. Oral opening was measured before and after treatments. results: The oral opening increased approximately 1 mm per treatment in three patients. One patient had temporomandibular joint symptoms of locking and did not have any increase in mouth opening. All four patients felt softening of the perioral skin, and all four patients described that articulation, eating and tooth brushing had become easier.
IPL can be a new adjunctive alternative in the non-surgical treatment of microstomia in patients with systemic sclerosis.
强脉冲光（IPL）治疗因诸如光嫩肤等用途而广为人知，其中使用了更高截止滤光片。较长波长可更深地穿透真皮，导致胶原蛋白受损并刺激新的胶原蛋白形成，从而使皮肤更柔软且更有弹性。系统性硬化症中的小口畸形是胶原蛋白过度沉积的最终结果，这使得口周皮肤紧实。患者在进行口腔自我护理时存在困难，甚至专业的牙科护理也可能变得复杂。
对4例患有系统性硬化症和小口畸形的患者在口周区域进行了强脉冲光（丹麦Ellipse A/S Flex系统）治疗。患者接受了3 - 5次治疗，间隔为4周。在治疗前后测量开口度。结果：3例患者每次治疗后开口度大约增加1毫米。1例患者有颞下颌关节锁定症状，开口度未增加。所有4例患者都感觉口周皮肤变软，并且所有4例患者均表示发音、进食和刷牙变得更容易了。
强脉冲光可成为系统性硬化症患者小口畸形非手术治疗中的一种新的辅助选择。
