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[半规管的感受器功能。第2部分:病理生理学、疾病、临床发现及治疗方面]

[Receptor function of the semicircular canals. Part 2: pathophysiology, diseases, clinical findings and treatment aspects].

作者信息

Blödow A, Bloching M, Hörmann K, Walther L E

机构信息

HNO-Klinik, Helios-Klinikum Berlin-Buch, Berlin, Deutschland.

出版信息

HNO. 2012 Mar;60(3):249-59; quiz 260-1. doi: 10.1007/s00106-011-2438-1.

DOI:10.1007/s00106-011-2438-1
PMID:22402905
Abstract

Perturbation of semicircular canal function may result in a pathological angular vestibulo-ocular reflex (aVOR). The resulting impairment in gaze stabilization is perceived as "vertigo" or "dizziness" and may occur following receptor function impairment of all three semicircular canals. The head impulse test reveals hidden (covert-catchup) or visible (overt-catchup) saccades in disturbances of semicircular function. Most peripheral vestibular disorders can be treated conservatively. There are surgical treatment options for some diseases, such as intractable benign paroxysmal positional vertigo and superior semicircular canal dehiscence. Vestibular training promotes central reorganization of the VOR. Impaired semicircular receptor function, in particular bilateral vestibulopathy, may affect spatial orientation and cognitive processes. Balance prostheses could serve as a replacement for receptors in the future.

摘要

半规管功能紊乱可能导致病理性角前庭眼反射(aVOR)。由此导致的注视稳定功能受损会被感知为“眩晕”或“头晕”,并且可能在所有三个半规管的感受器功能受损后出现。头部脉冲试验可揭示半规管功能障碍时隐藏的(隐蔽性追赶)或明显的(显性追赶)扫视。大多数外周前庭疾病可以保守治疗。对于一些疾病,如难治性良性阵发性位置性眩晕和上半规管裂,有手术治疗选择。前庭训练可促进VOR的中枢重组。半规管感受器功能受损,尤其是双侧前庭病,可能会影响空间定向和认知过程。未来,平衡假体可以替代感受器。

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本文引用的文献

1
Does my dizzy patient have a stroke? A systematic review of bedside diagnosis in acute vestibular syndrome.我的头晕患者是中风了吗?急性前庭综合征床边诊断的系统评价。
CMAJ. 2011 Jun 14;183(9):E571-92. doi: 10.1503/cmaj.100174. Epub 2011 May 16.
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Central oculomotor disturbances and nystagmus: a window into the brainstem and cerebellum.中脑眼运动障碍和眼球震颤:揭示脑桥和小脑的窗口。
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Vestibular function after acute vestibular neuritis.急性前庭神经炎后的前庭功能。
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Long-term course of Menière's disease revisited.梅尼埃病的长期病程再探讨。
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8
HINTS to diagnose stroke in the acute vestibular syndrome: three-step bedside oculomotor examination more sensitive than early MRI diffusion-weighted imaging.急性前庭综合征中诊断卒中的HINTS:三步床边动眼神经检查比早期MRI弥散加权成像更敏感
Stroke. 2009 Nov;40(11):3504-10. doi: 10.1161/STROKEAHA.109.551234. Epub 2009 Sep 17.
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Long-term follow-up of vestibular neuritis.前庭神经炎的长期随访
Ann N Y Acad Sci. 2009 May;1164:427-9. doi: 10.1111/j.1749-6632.2008.03721.x.
10
Head-shaking nystagmus in central vestibulopathies.中枢性前庭病变中的摇头性眼球震颤。
Ann N Y Acad Sci. 2009 May;1164:338-43. doi: 10.1111/j.1749-6632.2008.03737.x.