Department of Psychology, University of Texas at Austin, 78712, USA.
Ann Behav Med. 2012 Jun;43(3):352-61. doi: 10.1007/s12160-011-9338-1.
Antidepressants can impair sexual arousal. Exercise increases genital arousal in healthy women, likely due to increasing sympathetic nervous system (SNS) activity.
Test if exercise increases genital arousal in women taking antidepressants, including selective serotonin reuptake inhibitors (SSRIs), which suppress SNS activity, and selective serotonin and norepinephrine reuptake inhibitors (SNRIs), which suppress the SNS less.
Women reporting antidepressant-related sexual arousal problems (N = 47) participated in three counterbalanced sessions where they watched an erotic film while we recorded genital and SNS arousal. In two sessions, women exercised for 20 min, either 5 or 15 min prior to the films.
During the no-exercise condition, women taking SSRIs showed significantly less genital response than women taking SNRIs. Exercise prior to sexual stimuli increased genital arousal in both groups. Women reporting greater sexual dysfunction had larger increases in genital arousal post-exercise. For women taking SSRIs, genital arousal was linked to SNS activity.
Exercise may improve antidepressant-related genital arousal problems.
抗抑郁药会影响性唤起。运动可增加健康女性的生殖器唤起，可能是由于增加了交感神经系统（SNS）的活动。
测试运动是否会增加服用抗抑郁药（包括选择性 5-羟色胺再摄取抑制剂 [SSRIs]，其抑制 SNS 活性，以及选择性 5-羟色胺和去甲肾上腺素再摄取抑制剂 [SNRIs]，其对 SNS 的抑制作用较小）的女性的生殖器唤起。
报告抗抑郁药相关的性唤起问题的女性（N=47）参加了三个平衡对照的会议，在观看色情电影的同时，我们记录了生殖器和 SNS 的唤醒。在两次会议中，女性都进行了 20 分钟的运动，要么在电影前 5 分钟，要么在电影前 15 分钟。
在不运动的情况下，服用 SSRIs 的女性的生殖器反应明显低于服用 SNRIs 的女性。在性刺激前运动可增加两组的生殖器唤起。报告性功能障碍较大的女性在运动后生殖器唤起的增加幅度更大。对于服用 SSRIs 的女性，生殖器唤起与 SNS 活动有关。
运动可能改善抗抑郁药相关的生殖器唤起问题。
