Ried L D, Christensen D B, Stergachis A
School of Pharmacy, University of Washington, Seattle 98195.
Am J Public Health. 1990 Nov;80(11):1349-53. doi: 10.2105/ajph.80.11.1349.
The purpose of this study was to investigate medical and psychosocial factors that may be used to identify patients at risk of psychotropic drug use. Population-based surveys were completed by 278 elderly health maintenance organization (HMO) patients in August 1984. Physical and mental health status and social support were measured in the survey. Automated prescription records from the year prior to and the year after the survey were linked to data from the survey. Patients received 737 prescriptions for psychotropic drugs during the two-year period under study. Doxepin (20.2 percent), flurazepam (15.2 percent), and diazepam (14.8 percent) were dispensed most frequently. Nearly 30 percent of the patients received a prescription for at least one psychotropic drug during the two-year period, and 14 percent received at least one prescription during both years. Three significant predictors of subsequent psychotropic drug use were: prior use (odds ratio = 17.2, 95% CI = 6.25, 47.33), the number of physical impairments (OR = 1.73, 95% CI = 1.05, 2.84), and the respondent's rating on the Alameda Health Scale (OR = 1.65, 95% CI = 0.99, 2.75). Patients' self-reported mental health status and sociodemographic characteristics were not significant predictors of subsequent use.
本研究的目的是调查可用于识别有使用精神药物风险的患者的医学和社会心理因素。1984年8月,278名老年健康维护组织(HMO)患者完成了基于人群的调查。调查中测量了身心健康状况和社会支持情况。将调查前一年和调查后一年的自动处方记录与调查数据相链接。在研究的两年期间,患者共收到737张精神药物处方。多虑平(20.2%)、氟西泮(15.2%)和地西泮(14.8%)的处方开具最为频繁。近30%的患者在两年期间至少收到过一张精神药物处方,14%的患者在这两年中每年至少收到一张处方。后续使用精神药物的三个显著预测因素为:既往使用情况(优势比=17.2,95%置信区间=6.25,47.33)、身体损伤数量(优势比=1.73,95%置信区间=1.05,2.84)以及受访者在阿拉米达健康量表上的评分(优势比=1.65,95%置信区间=0.99,2.75)。患者自我报告的心理健康状况和社会人口学特征并非后续使用的显著预测因素。