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美国阿拉巴马州两栖类和爬行类动物中东部马脑炎病毒的血清学监测

Serosurveillance of eastern equine encephalitis virus in amphibians and reptiles from Alabama, USA.

机构信息

Department of Biological Sciences, Auburn University, Alabama, USA.

出版信息

Am J Trop Med Hyg. 2012 Mar;86(3):540-4. doi: 10.4269/ajtmh.2012.11-0283.

Abstract

Eastern equine encephalitis virus (EEEV) is among the most medically important arboviruses in North America, and studies suggest a role for amphibians and reptiles in its transmission cycle. Serum samples collected from 351 amphibians and reptiles (27 species) from Alabama, USA, were tested for the presence of antibodies against EEEV. Frogs, turtles, and lizards showed little or no seropositivity, and snakes had high seropositivity rates. Most seropositive species were preferred or abundant hosts of Culex spp. mosquitoes at Tuskegee National Forest, that target ectothermic hosts. The cottonmouth, the most abundant ectotherm sampled, displayed a high prevalence of seropositivity, indicating its possible role as an amplification and/or over-wintering reservoir for EEEV.

摘要

东部马脑炎病毒(EEEV)是北美的医学最重要的虫媒病毒之一,研究表明两栖类和爬行类动物在其传播周期中发挥作用。从美国阿拉巴马州采集的 351 份两栖类和爬行类动物(27 种)血清样本中检测了针对 EEEV 的抗体。青蛙、海龟和蜥蜴的血清阳性率较低或为阴性,而蛇的血清阳性率较高。在塔斯基吉国家森林,大多数血清阳性的物种都是库蚊的首选或丰富宿主,而库蚊的目标是冷血动物宿主。棉口蛇,采样中最丰富的冷血动物,表现出高的血清阳性率,表明其可能作为 EEEV 的扩增和/或越冬库。

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