Thong S, Hooper W, Xu Y, Ghassemi A, Winston A
Church & Dwight Co. Inc., Princeton, NJ, USA.
J Clin Dent. 2011;22(5):171-8.
To determine if baking soda toothpastes are relatively more effective than non-baking soda toothpastes in promoting plaque removal from less accessible sites in the dentition.
Several single-brushing comparisons of baking soda and non-baking soda toothpastes for their overall ability to remove plaque have been published. In this study, individual comparisons of these published data, comparing the plaque removal performance of baking soda and non-baking soda toothpastes at various sites in the dentition, were examined to see if there were any site-dependant performance trends. The site-specific single-brushing data were then combined and analyzed in two ways. Meta-analyses of the clinical studies were performed to compare baking soda's relative plaque removal advantage at various sites in the mouth using paired t-testing at p <0.05. Also, plaque index reductions at various sites due to brushing with baking soda toothpastes were graphically compared with plaque index reductions due to brushing with non-baking soda dentifrices. The percent relative plaque removal advantage for baking soda toothpastes at various sites were plotted against the reduction in plaque index due to brushing with non-baking soda toothpastes.
Individual comparisons showed that brushing with the toothpastes containing baking soda generally removed significantly more plaque from each site than brushing with toothpastes without baking soda. The relative efficacy advantage for baking soda toothpastes was consistently higher at sites where the non-baking soda toothpastes removed less plaque. Meta-analytical comparisons confirmed baking soda toothpastes to be relatively more effective in enhancing plaque removal from sites where less plaque was removed compared to brushing with non-baking soda toothpastes (p < 0.05). Graphically, the baking soda toothpastes' relative plaque removal advantage could be seen to increase hyperbolically with decreasing plaque removal by the non-baking soda toothpastes with which they were compared. We presuppose that the reason less plaque is removed by non-baking soda toothpastes at some sites than others is that these sites are less accessible to the toothbrush.
These results show that baking soda toothpastes are relatively more effective in enhancing plaque removal from harder-to-reach areas of the dentition (p <0.05), i.e., from lingual than facial surfaces, from posterior than anterior areas, and from proximal than mid-surface sites.
确定小苏打牙膏在促进清除牙列中较难触及部位的牙菌斑方面是否比非小苏打牙膏更有效。
已经发表了几项关于小苏打牙膏和非小苏打牙膏清除牙菌斑总体能力的单组刷牙比较研究。在本研究中,对这些已发表数据进行个体比较,比较小苏打牙膏和非小苏打牙膏在牙列各个部位的牙菌斑清除性能,以查看是否存在任何部位依赖性性能趋势。然后将特定部位的单组刷牙数据以两种方式进行合并和分析。进行临床研究的荟萃分析,使用配对t检验(p<0.05)比较小苏打在口腔各个部位相对的牙菌斑清除优势。此外,将使用小苏打牙膏刷牙导致的各个部位牙菌斑指数降低情况与使用非小苏打牙膏刷牙导致的牙菌斑指数降低情况进行了图表比较。将小苏打牙膏在各个部位相对的牙菌斑清除优势百分比与使用非小苏打牙膏刷牙导致的牙菌斑指数降低情况进行了绘图。
个体比较表明,使用含小苏打牙膏刷牙通常比使用不含小苏打牙膏刷牙从每个部位清除的牙菌斑明显更多。在非小苏打牙膏清除牙菌斑较少的部位,小苏打牙膏的相对功效优势始终更高。荟萃分析比较证实,与使用非小苏打牙膏刷牙相比,小苏打牙膏在增强从牙菌斑清除较少部位清除牙菌斑方面相对更有效(p<0.05)。从图表上看,可以看到小苏打牙膏的相对牙菌斑清除优势随着与其比较的非小苏打牙膏清除牙菌斑量的减少而呈双曲线增加。我们预先假定,非小苏打牙膏在某些部位比其他部位清除的牙菌斑少的原因是这些部位牙刷难以触及。
这些结果表明,小苏打牙膏在增强从牙列中较难到达的区域(p<0.05)清除牙菌斑方面相对更有效,即从舌面比从唇面、从后部比从前部区域、从邻面比从中面部位清除牙菌斑更有效。