Zhang Yan, Mei Tonghua, Wu Zezhi
Department of Respiratory, Second Affiliated Hospital of Chongqing Medicine University, Chongqing 400010, China.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 2012 Feb;29(1):134-6.
The present paper was aimed to explore the effect of Shuxuetong on the membrane viscoelasticity of erythrocyte taken from the acute phase patients suffering from chronic pulmonary heart disease. The membrane viscoelasticity of erythrocyte was taken from the acute phase patients suffering from chronic pulmonary heart disease. The changes of membrane viscoelasticity of erythrocyte after treated with shuxuetong were detected by micropipette aspiration technique. The results showed that the Shuxuetong of certain concentration could cause the decrease of membrane elastic modulus and viscous coefficients in acute phase patients suffering from chronic pulmonary heart disease. The study offers experimental evidences that the comprehensive treatment of pulmonary heart disease should involve the drug or measure to improve the erythrocyte deformability.
本研究旨在探讨舒血宁对慢性肺心病急性期患者红细胞膜黏弹性的影响。红细胞膜黏弹性取自慢性肺心病急性期患者。采用微量吸管吸液技术检测舒血宁处理后红细胞膜黏弹性的变化。结果表明，一定浓度的舒血宁可使慢性肺心病急性期患者的膜弹性模量和黏性系数降低。该研究为肺心病综合治疗应包括改善红细胞变形能力的药物或措施提供了实验依据。
