早产儿吸氧的证据。
Evidence for oxygen use in preterm infants.
机构信息
Division of Neonatology, Rainbow Babies & Childrens Hospital, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH 44106, USA.
出版信息
Acta Paediatr. 2012 Apr;101(464):29-33. doi: 10.1111/j.1651-2227.2011.02548.x.
AIM
To review the evidence for optimal oxygen use in preterm infants.
RESULTS
Clinicians have embraced lower saturation targets to minimize retinopathy of prematurity (ROP). Large randomized trials now have shown that while such targets reduce ROP, neonatal mortality is increased significantly.
CONCLUSIONS
Preterm infants should be resuscitated with blended oxygen (30-90%) targeted to avoid hyperoxia. Later, saturation management remains uncertain. Until ongoing trials and follow-up are complete, it is prudent to avoid saturation of 85-89%.
目的
回顾早产儿最佳氧疗的证据。
结果
临床医生已接受更低的饱和度目标以尽量减少早产儿视网膜病变（ROP）。目前大型随机试验表明，尽管这些目标降低了 ROP，但新生儿死亡率显著增加。
结论
早产儿应接受混合氧（30-90%）复苏以避免高氧血症。之后，饱和度管理仍不确定。在正在进行的试验和随访完成之前，避免饱和度达到 85-89%是明智的。
Zotero 插件