Department of Cardiothoracic Surgery, Catharina Hospital, Eindhoven, the Netherlands.
J Cardiothorac Vasc Anesth. 2012 Aug;26(4):617-23. doi: 10.1053/j.jvca.2012.01.022. Epub 2012 Mar 8.
The EuroSCORE as a predictor for midterm survival after isolated aortic valve replacement (AVR) and combined AVR with coronary artery bypass graft (CABG) surgery was tested. Survival in different risk-stratification groups also was compared to the survival of the general Dutch population.
A retrospective analysis of prospectively collected data.
A single-center study performed in an educational hospital.
All patients (N = 1,652) who underwent AVR with (n = 711) or without (n = 941) CABG surgery from January 2004 through December 2009.
AVR with or without CABG surgery.
Univariate Cox regression analyses were used to identify the additive and the logistic EuroSCOREs as independent predictors of midterm mortality. Kaplan-Meier survival curves were used to compare the survival of different patients' risk subgroups, based on both the additive and the logistic EuroSCOREs, with the normal Dutch population matched for age and sex. Both additive and logistic EuroSCOREs were significant predictors of midterm mortality after isolated AVR and AVR with CABG surgery. This was also true for the different risk-stratification groups. Except for survival after AVR with CABG surgery in the high-risk group based on the additive EuroSCORE, no difference was found between survival after surgery and survival of the age- and sex-matched normal population.
Both EuroSCORE models can predict midterm survival after isolated AVR and combined AVR with CABG surgery. However, the EuroSCORE is not a predictor for midterm survival when comparing the patient groups with the general Dutch population matched for age and sex. Except for high-risk patients undergoing AVR with CABG surgery, other risk subgroups have similar midterm survival to that of their age- and sex-matched cohorts of the Dutch population.
测试 EuroSCORE 作为孤立主动脉瓣置换术（AVR）和 AVR 联合冠状动脉旁路移植术（CABG）术后中期生存的预测因子。还将比较不同风险分层组的生存率与荷兰普通人群的生存率。
前瞻性收集数据的回顾性分析。
在一家教学医院进行的单中心研究。
2004 年 1 月至 2009 年 12 月期间接受 AVR 加（n = 711）或不加（n = 941）CABG 手术的所有患者。
AVR 加或不加 CABG 手术。
使用单变量 Cox 回归分析来确定加性和逻辑 EuroSCORE 作为中期死亡率的独立预测因子。使用 Kaplan-Meier 生存曲线比较基于加性和逻辑 EuroSCORE 的不同患者风险亚组的生存情况，与年龄和性别匹配的正常荷兰人群进行比较。加性和逻辑 EuroSCORE 都是孤立 AVR 和 AVR 联合 CABG 手术后中期死亡率的显著预测因子。这对不同的风险分层组也是如此。除了基于加性 EuroSCORE 的高危组 CABG 手术后的生存外，手术后的生存与年龄和性别匹配的正常人群的生存之间没有差异。
两种 EuroSCORE 模型都可以预测孤立 AVR 和 AVR 联合 CABG 手术后的中期生存率。然而，当将患者组与年龄和性别匹配的普通荷兰人群进行比较时，EuroSCORE 并不是中期生存率的预测因子。除了高危患者接受 CABG 手术的 AVR 外，其他风险亚组的中期生存率与荷兰人群中年龄和性别匹配的队列相似。
