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年轻男性洛伊兹-迪茨综合征患者的双侧腘动脉动脉瘤。

Bilateral popliteal artery aneurysms in a young man with Loeys-Dietz syndrome.

机构信息

Department of Vascular Surgery, King's College Hospital, London, United Kingdom.

出版信息

J Vasc Surg. 2012 Aug;56(2):486-8. doi: 10.1016/j.jvs.2012.01.064. Epub 2012 Mar 9.

Abstract

Loeys-Dietz syndrome is a recently described genetic connective tissue disorder. The syndrome is associated with multiple nonvascular phenotypic anomalies but also aggressive arteriopathy, which has so far principally been shown to cause aortic root dilatation with subsequent dissection and rupture. We report the first ever case of a young man diagnosed with Loeys-Dietz syndrome with asymptomatic large bilateral popliteal artery aneurysms. We have successfully resected these aneurysms and revascularized with synthetic graft.

摘要

Loeys-Dietz 综合征是一种新近描述的遗传性结缔组织疾病。该综合征与多种非血管表型异常相关,但也与侵袭性动脉疾病相关,目前主要表现为导致主动脉根部扩张,继而出现夹层和破裂。我们报告首例年轻男性确诊的 Loeys-Dietz 综合征患者,伴有无症状的双侧巨大腘动脉瘤。我们成功切除了这些动脉瘤,并使用合成移植物进行了再血管化。

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