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单囊性成釉细胞瘤的袋形术:一种针对侵袭性牙源性肿瘤的保守治疗方法。

Marsupialization of unicystic ameloblastoma: a conservative approach for aggressive odontogenic tumors.

作者信息

Dolanmaz Dogan, Etoz Osman A, Pampu Alper, Kalayci Abdullah, Gunhan Omer

机构信息

Department of Oral and Maxillofacial Surgery, Erciyes University, Kayseri, Turkey.

出版信息

Indian J Dent Res. 2011 Sep-Oct;22(5):709-12. doi: 10.4103/0970-9290.93461.

DOI:10.4103/0970-9290.93461
PMID:22406718
Abstract

Unicystic ameloblastoma (UA) is known as a distinct entity which has a less aggressive behavior when compared with conventional ameloblastoma. In this report, we have presented two cases of UAs, (of which one case showed a more aggressive behavior with mural invasion into the adjacent tissues and granular cell differentiation), both of which were successfully managed with enucleation following marsupialization. We aim to highlight how this method can be used for the successful management of such cases, rather than following more aggressive approaches. In both the cases, marsupialization was done for the UA lesions initially and follow-ups were maintained. When the tumor size had regressed on radiographic follow up, an enucleation procedure with ostectomy of the margins was carried out. Special importance was also given to the endodontic treatment of the teeth involved in the area of the lesion. The patients were free of the condition and did not show any signs of recurrence on radiographic follow-ups even after 30 months of the final procedure. Granular variant of UA is quite rare and had been considered to be more aggressive. Marsupialization of UA is an alternative treatment option of resection even for more aggressive variants, as long as the histological behavior of the lesion was carefully evaluated and strict radiographic follow-up is maintained.

摘要

单囊性成釉细胞瘤(UA)是一种独特的实体瘤,与传统成釉细胞瘤相比,其侵袭性较小。在本报告中,我们展示了两例UA病例,(其中一例表现出更具侵袭性的行为,伴有壁层侵犯相邻组织和颗粒细胞分化),两例均在袋形术之后成功地通过摘除术进行了治疗。我们旨在强调这种方法如何能够成功地用于治疗此类病例,而不是采用更激进的方法。在这两例病例中,最初对UA病变进行了袋形术,并进行了随访。当肿瘤大小在影像学随访中缩小后,进行了边缘骨切除术的摘除术。对病变区域涉及的牙齿的牙髓治疗也给予了特别重视。即使在最后一次手术后30个月,患者的病情已痊愈,影像学随访中也未显示任何复发迹象。UA的颗粒状变体相当罕见,曾被认为更具侵袭性。UA的袋形术是一种替代切除的治疗选择,即使对于更具侵袭性的变体也是如此,只要仔细评估病变的组织学行为并保持严格的影像学随访。

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