Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory, Sun Yat-Sen University, Guangzhou, China.
Key Laboratory of Oral Medicine, Guangzhou Institute of Oral Disease, Stomatology Hospital of Guangzhou Medical University, Guangzhou, China.
Head Neck. 2018 Oct;40(10):2172-2180. doi: 10.1002/hed.25212. Epub 2018 May 13.
This retrospective study investigated the reduction rate and speed of shrinkage after marsupialization in mandibular cystic ameloblastoma and clarified whether marsupialization is appropriate for unicystic ameloblastoma and multicystic ameloblastoma.
Sixty-three patients with mandibular cystic ameloblastoma were initially treated with marsupialization. Premarsupialization and postmarsupialization panoramic radiographs were reviewed for reduction rate and speed of shrinkage, and then were evaluated with age, sex, tumor location, and tumor type.
The overall recurrence rate was 4.5% (2/44). The average reduction rate after marsupialization was 65.6%. No significant difference was found between unicystic ameloblastoma and multicystic ameloblastoma in reduction rate. The speed of shrinkage of unicystic ameloblastoma was significantly faster than that of multicystic ameloblastoma (P < .05). Similarly, patients with multicystic ameloblastoma had longer marsupialization periods than those with unicystic ameloblastoma (P < .05).
Marsupialization is effective in reducing tumor size for both unicystic ameloblastoma and multicystic ameloblastoma. Marsupialization plus second-stage curettage is recommended as the primary treatment for mandibular cystic ameloblastoma.
本回顾性研究调查了下颌骨囊性成釉细胞瘤经袋形手术治疗后的缩小率和缩小速度，并阐明了袋形手术是否适用于单囊型成釉细胞瘤和多囊型成釉细胞瘤。
63 例下颌骨囊性成釉细胞瘤患者最初接受了袋形手术治疗。对术前和术后的全景片进行了缩小率和缩小速度的评估，并根据年龄、性别、肿瘤位置和肿瘤类型进行了评价。
总的复发率为 4.5%（2/44）。袋形手术后的平均缩小率为 65.6%。单囊型成釉细胞瘤和多囊型成釉细胞瘤的缩小率无显著差异。单囊型成釉细胞瘤的缩小速度明显快于多囊型成釉细胞瘤（P<.05）。同样，多囊型成釉细胞瘤的袋形手术时间也长于单囊型成釉细胞瘤（P<.05）。
袋形手术对单囊型和多囊型成釉细胞瘤均有效，可以减少肿瘤大小。对于下颌骨囊性成釉细胞瘤，推荐采用袋形手术联合二期刮除术作为主要治疗方法。
