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成人和儿童高等级脊椎滑脱症手术相关的短期并发症:来自脊柱侧凸研究学会发病率和死亡率数据库的报告。

Short-term complications associated with surgery for high-grade spondylolisthesis in adults and pediatric patients: a report from the scoliosis research society morbidity and mortality database.

机构信息

University of Virginia Medical Center, Department of Neurosurgery, Charlottesville, VA 22908, USA.

出版信息

Neurosurgery. 2012 Jul;71(1):109-16. doi: 10.1227/NEU.0b013e3182535881.

DOI:10.1227/NEU.0b013e3182535881
PMID:22407074
Abstract

BACKGROUND

Although it is generally agreed upon that surgery for high-grade spondylolisthesis (HGS) is associated with more complications than low-grade spondylolisthesis, its description is primarily based on case reports and relatively small case series.

OBJECTIVE

To assess short-term complication rates associated with the surgical treatment of HGS in pediatric and adult patients and to identify factors associated with increased complication rates.

METHODS

All cases of HGS from the Scoliosis Research Society Morbidity and Mortality database for the year 2007 were reviewed. Patients were classified as pediatric (≤18 years) or adult (>18 years). Complications were tabulated, and the rates were compared between the patient groups and based on clinical and surgical factors.

RESULTS

165 cases of HGS were reported (88 pediatric, 77 adult). There were 49 complications (29.7%) in 41 patients (24.8%), with no difference in the proportions of pediatric vs adult patients with a complication (P = .86). Occurrence of new neurological deficit after surgery was the most common complication, seen in 19 (11.5%) patients. Performance of an osteotomy was associated with a higher incidence of new neurological deficits in both adult and pediatric groups (P = .02 and P = .012, respectively). Although most of the new neurological deficits improved over follow-up, 10% had no improvement.

CONCLUSION

This study provides short-term complication rates associated with surgical treatment for HGS in adult and pediatric patients and may prove valuable for patient counseling, surgical planning, and in efforts to improve the safety of patient care.

摘要

背景

尽管普遍认为,高级别脊椎滑脱症(HGS)的手术比低度脊椎滑脱症相关的并发症更多,但对其的描述主要基于病例报告和相对较小的病例系列。

目的

评估小儿和成人患者接受 HGS 手术治疗的短期并发症发生率,并确定与并发症发生率增加相关的因素。

方法

回顾 2007 年脊柱侧凸研究学会发病率和死亡率数据库中所有 HGS 病例。患者分为小儿(≤18 岁)或成人(>18 岁)。列出并发症,并比较两组患者之间以及基于临床和手术因素的并发症发生率。

结果

报告了 165 例 HGS(88 例小儿,77 例成人)。41 例患者(24.8%)出现 49 种并发症(29.7%),小儿和成人患者并发症发生率无差异(P =.86)。手术后出现新的神经功能缺损是最常见的并发症,见于 19 例(11.5%)患者。在成人和小儿组中,进行截骨术与新的神经功能缺损发生率较高相关(P =.02 和 P =.012,分别)。尽管大多数新的神经功能缺损在随访中得到改善,但 10%的患者没有改善。

结论

本研究提供了小儿和成人患者接受 HGS 手术治疗的短期并发症发生率,可能对患者咨询、手术计划以及努力提高患者护理安全性具有重要意义。

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