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精神分裂症快感缺失的新视角。

A new perspective on anhedonia in schizophrenia.

机构信息

Department of Psychiatry and the Mary land Psychiatric Research Center, Unive rsity of Mary land School of Medicine, Baltimore, USA.

出版信息

Am J Psychiatry. 2012 Apr;169(4):364-73. doi: 10.1176/appi.ajp.2011.11030447.

DOI:10.1176/appi.ajp.2011.11030447
PMID:22407079
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3732829/
Abstract

OBJECTIVE

Previous research provides evidence for discrepancies in various types of emotional self-report in individuals with schizophrenia; patients and healthy subjects report similar levels of positive emotion when reporting current feelings, yet patients report lower levels of positive emotion when reporting on noncurrent feelings. Such apparent discrepancies, which have come to be termed the "emotion paradox" in schizophrenia, have complicated our understanding of what anhedonia actually reflects in this patient population. The authors sought to resolve this paradox.

METHOD

The authors reviewed the empirical literature on anhedonia and emotional experience in schizophrenia through the lens of the accessibility model of emotional self-report, a well-validated model of emotional self-report developed in the affective science literature that clarifies the sources of emotion knowledge that individuals access when providing different types of self-report. The authors used this model to propose a resolution to the "emotion paradox" and to provide a new psychological conceptualization of anhedonia.

RESULTS

Data are presented in support of this new perspective on anhedonia and to demonstrate how cognitive impairments may influence reports of noncurrent feelings in schizophrenia.

CONCLUSIONS

The authors conclude that anhedonia should no longer be considered an experiential deficit or a diminished "capacity" for pleasure in patients with schizophrenia. Rather, anhedonia reflects a set of beliefs related to low pleasure that surface when patients are asked to report their noncurrent feelings. Encoding and retrieval processes may serve to maintain these beliefs despite contrary real-world pleasurable experiences. Implications for assessment and treatment are discussed in relation to this new conceptualization of anhedonia.

摘要

目的

先前的研究为精神分裂症个体在各种类型的情感自我报告中存在差异提供了证据;患者和健康受试者在报告当前感受时报告了相似水平的积极情绪,但在报告非当前感受时报告的积极情绪水平较低。这种明显的差异,在精神分裂症中被称为“情绪悖论”,使我们对快感缺失在这一患者群体中实际反映的情况更加难以理解。作者试图解决这一悖论。

方法

作者通过情感自我报告的可及性模型来审查快感缺失和精神分裂症中的情感体验的实证文献,这是情感科学文献中提出的一种经过充分验证的情感自我报告模型,该模型阐明了个体在提供不同类型的自我报告时所获取的情感知识的来源。作者使用该模型来提出解决“情绪悖论”的方法,并提供快感缺失的新的心理学概念化。

结果

提出了支持这种新的快感缺失观点的数据,并展示了认知障碍如何影响精神分裂症患者的非当前感受报告。

结论

作者得出结论,快感缺失不应再被视为精神分裂症患者的体验缺陷或愉悦“能力”降低。相反,快感缺失反映了一组与低愉悦相关的信念,这些信念在患者被要求报告他们的非当前感受时浮现出来。尽管存在相反的现实愉悦体验,但编码和检索过程可能有助于维持这些信念。本文讨论了与快感缺失这种新的概念化相关的评估和治疗的意义。

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本文引用的文献

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Schizophr Bull. 2013 Jan;39(1):217-25. doi: 10.1093/schbul/sbr137. Epub 2011 Oct 20.
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Randomized trial to evaluate the efficacy of cognitive therapy for low-functioning patients with schizophrenia.评估认知疗法对低功能精神分裂症患者疗效的随机试验。
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Patterns of emotional experience in schizophrenia: differences in emotional response to visual stimuli are associated with clinical presentation and functional outcome.
精神分裂症中努力分配受损。
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Rethinking psychiatric symptoms: the role of measurement heterogeneity in diagnostic validity.重新审视精神症状:测量异质性在诊断效度中的作用。
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Reward Processing in Mood Disorders and Schizophrenia: A Neurodevelopmental Framework.情绪障碍与精神分裂症中的奖赏处理:一个神经发育框架
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Addressing Altered Anticipation as a Transdiagnostic Target Through Computational Psychiatry.通过计算精神病学将改变的预期作为跨诊断靶点来解决。
Biol Psychiatry Cogn Neurosci Neuroimaging. 2025 Mar 7. doi: 10.1016/j.bpsc.2025.02.014.
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Characterizing the Profile of Anhedonia in Individuals With Schizotypal Traits, Subthreshold Depression and Autistic Traits.对具有分裂型特质、亚阈抑郁和自闭症特质个体的快感缺失特征进行描述。
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Anhedonia Across and Beyond the Schizophrenia Spectrum.精神分裂症谱系及以外的快感缺失
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Social anhedonia in the daily lives of people with schizophrenia: Examination of anticipated and consummatory pleasure.精神分裂症患者日常生活中的社交快感缺失:预期和享受乐趣的考察。
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