Suppr超能文献

犬模型中手动经喉喷射通气与误吸风险

Manual translaryngeal jet ventilation and the risk of aspiration in a canine model.

作者信息

Yealy D M, Plewa M C, Reed J J, Kaplan R M, Ilkhanipour K, Stewart R D

机构信息

Division of Emergency Medicine, University of Pittsburgh, Pennsylvania.

出版信息

Ann Emerg Med. 1990 Nov;19(11):1238-41. doi: 10.1016/s0196-0644(05)82280-2.

Abstract

STUDY OBJECTIVES

Manual translaryngeal jet ventilation (TLJV) is a safe and effective method of maintaining normal ventilation in apneic subjects. Little data exist on the amount of airway protection afforded with this technique of airway management. We sought to evaluate the risk of aspiration during manual TLJV.

SETTING

Data were collected in a laboratory animal model.

DESIGN

A prospective, nonrandomized, controlled trial was performed.

PARTICIPANTS

Seventeen adult apneic mongrel dogs were enrolled.

INTERVENTIONS

Intratracheal Gastrograffin was instilled and radiographic changes assessed during ventilation using a 0 to 3 scale (none to severe). Thirty-six trials were performed, with equal numbers at both 30 degrees and 45 degrees head elevation. The three groups studied were animals without airway protection (control), animals with a cuffed endotracheal tube (tube), and animals with a percutaneous TLJV cannula and a 50-psi oxygen source ventilated at a rate of 20 breaths per minute (jet).

MEASUREMENTS AND MAIN RESULTS

Significantly less radiographic evidence of aspiration was noted in the jet and tube groups at 30 degrees and 45 degrees compared with control animals (P = .002 each). At 45 degrees head elevation a trend toward increased aspiration scores in the jet group compared with the tube group (P = .065) was observed.

CONCLUSION

In our model, manual TLJV at 20 breaths per minute and an I:E ratio of 1:2 provided protection from aspiration comparable to that observed with a cuffed endotracheal tube at 30 degrees head elevation. At 45 degrees elevation, this protection was diminished.

摘要

研究目的

手动经喉喷射通气(TLJV)是在呼吸暂停患者中维持正常通气的一种安全有效的方法。关于这种气道管理技术所提供的气道保护程度的数据很少。我们试图评估手动TLJV期间误吸的风险。

设置

在实验室动物模型中收集数据。

设计

进行了一项前瞻性、非随机、对照试验。

参与者

纳入了17只成年呼吸暂停杂种犬。

干预措施

注入气管内泛影葡胺,并在通气期间使用0至3级(无至严重)评估放射学变化。共进行了36次试验,头高位30度和45度时的试验次数相等。研究的三组分别是无气道保护的动物(对照组)、带套囊气管内导管的动物(导管组)和经皮TLJV套管且以每分钟20次呼吸频率使用50 psi氧气源通气的动物(喷射组)。

测量和主要结果

与对照组动物相比,喷射组和导管组在30度和45度时误吸的放射学证据明显更少(每组P = 0.002)。在头高位45度时,观察到喷射组与导管组相比误吸评分有增加的趋势(P = 0.065)。

结论

在我们的模型中,每分钟20次呼吸频率且吸呼比为1:2的手动TLJV提供的误吸保护与头高位30度时带套囊气管内导管所观察到的保护相当。在头高位45度时,这种保护作用减弱。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验