Department of Medical Bionanotechnology, Chettinad University, Chettinad Hospital and Research Institute (CHRI), Kelambakkam, Chennai, India.
Spectrochim Acta A Mol Biomol Spectrosc. 2012 Jun 15;92:29-32. doi: 10.1016/j.saa.2012.02.044. Epub 2012 Feb 20.
The present study reports the effect of cadmium sulfide (CdS) quantum dots on the life cycle of Escherichia coli. CdS quantum dots were synthesized by pH sensitive organochemical route using cadmium chloride and sodium sulfide as precursors and mercaptopropionic acid (MPA) as capping agent. It is observed that varying concentration of MPA leads to the production of different sized quantum dots with inverse proportionality and increment in the fluorescence quantum yield. The investigation also shows that CdS quantum dots have no antibacterial activity except it delays the log phase growth of bacteria in terms of size of the particles. The largest synthesized particles significantly elongate the lag phase growth.
本研究报告了硫化镉 (CdS) 量子点对大肠杆菌生命周期的影响。CdS 量子点通过 pH 敏感的有机化学途径合成,使用氯化镉和硫化钠作为前体,巯基丙酸 (MPA) 作为封端剂。结果表明,MPA 的浓度变化导致不同尺寸的量子点的产生,其荧光量子产率呈反比和递增关系。研究还表明,CdS 量子点除了在颗粒尺寸方面延迟细菌对数期的生长外,没有抗菌活性。最大合成的颗粒显著延长了迟滞期的生长。