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[经皮腔内冠状动脉成形术后再狭窄。临床与治疗方面]

[Restenosis after transluminal coronary angioplasty. Clinical and therapeutic aspects].

作者信息

Metzger J P, Tabone X, Le Feuvre C, Bénichou J M, Hajri S, Heulin A, Vacheron A

机构信息

Clinique Cardiologique, Hôpital Necker, Paris.

出版信息

Ann Med Interne (Paris). 1990;141(4):325-8.

PMID:2240944
Abstract

To assess the incidence and clinical presentation of restenosis after successful coronary angioplasty, and the short- and mid-term results of its treatment, 160 patients, who underwent a first coronary angioplasty between May 1987 and December 1988, were closely monitored. Restenosis is defined as a loss of 50% or more of the initial gain in area and/or 30% or more in diameter, or chronic coronary occlusion. These criteria were met in 43 patients (27%) within 5.1 months (1-6 months), on the average, after angioplasty. Restenosis was expressed as unstable angina in 51% of the patients, stable angina in 30%, and abnormal thallium myocardial scintigraphy under exercise in 14%. Myocardial infarction was never the revealing symptom. In 63% of the cases, the pain caused by restenosis repeated the initial angina. A second angioplasty was performed in 75% of the patients with a success rate of 93%, in the absence of an occlusion, and a 37% rate of further restenosis.

摘要

为评估成功进行冠状动脉血管成形术后再狭窄的发生率和临床表现,以及其治疗的短期和中期结果,对1987年5月至1988年12月期间首次接受冠状动脉血管成形术的160例患者进行了密切监测。再狭窄定义为初始面积增加丧失50%或更多和/或直径减少30%或更多,或慢性冠状动脉闭塞。血管成形术后平均5.1个月(1至6个月)内,43例患者(27%)符合这些标准。51%的患者再狭窄表现为不稳定型心绞痛,30%为稳定型心绞痛,14%为运动时铊心肌闪烁显像异常。心肌梗死从未作为首发症状出现。63%的病例中,再狭窄引起的疼痛与初始心绞痛相似。75%的患者接受了第二次血管成形术,在无闭塞的情况下成功率为93%,再次发生再狭窄的比例为37%。

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