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对吸入物和食物的超敏反应与平衡障碍。

Hypersensitivity to inhalants and food in balance disturbances.

作者信息

Cisi E Domingues, R Saraiva Moreira Bittar, Ferreira de Mello J

机构信息

Hospital das Clínicas of the School of Medicine of the University of São Paulo, São Paulo, Sao Paulo, Brazil.

出版信息

Rev Laryngol Otol Rhinol (Bord). 2011;132(2):81-4.

PMID:22416486
Abstract

INTRODUCTION

The prevalence of allergy in patients with Menière's disease was established as approximately 41.6% for inhalants and 26.6% for food. These are elevated values in relation to the prevalence of allergy in the general population, which varies from 9% to 30% for inhalants (in Brazil) and from 1% to 3% for food.

OBJECTIVES

To evaluate the prevalence of type I hypersensitivity reactions to inhalants and food in the patients of the Neurotology Sector of the "Hospital das Clinicas" of the University of São Paulo Medical School and to describe vestibular symptoms of these patients.

METHOD

Seventy-five patients with imbalance due to peripheral origin were evaluated by a questionnaire for the clinical characterization of the cochleo-vestibular symptoms and underwent the prick test for 13 inhalants and 5 food stuffs.

RESULTS

Twenty-five (33.3%) patients presented positive prick tests and, at least, one food allergen. Four patients presented positive prick tests without allergy symptoms. The prevalence of the complaint of rotatory dizziness was similar among the patients with positive and negative prick tests.

CONCLUSION

The prevalence of Type I hypersensitivity reactions to inhalants and food in the population evaluated was greater than in the general population. The vestibular symptoms did not differ among the patients with either positive or negative prick tests. However, a larger sample size should be obtained for the data to be more reliable and compared to a control group.

摘要

引言

梅尼埃病患者中吸入性过敏原的过敏患病率约为41.6%,食物过敏原的过敏患病率约为26.6%。与普通人群的过敏患病率相比,这些数值有所升高,普通人群中吸入性过敏原的过敏患病率在巴西为9%至30%,食物过敏原的过敏患病率为1%至3%。

目的

评估圣保罗大学医学院“临床医院”神经耳科学科患者中对吸入性过敏原和食物的I型超敏反应患病率,并描述这些患者的前庭症状。

方法

通过问卷调查对75例因外周原因导致失衡的患者进行耳蜗-前庭症状的临床特征评估,并对13种吸入性过敏原和5种食物进行点刺试验。

结果

25例(33.3%)患者点刺试验呈阳性,且至少对一种食物过敏原过敏。4例患者点刺试验呈阳性但无过敏症状。点刺试验阳性和阴性的患者中旋转性头晕主诉的患病率相似。

结论

在所评估人群中,对吸入性过敏原和食物的I型超敏反应患病率高于普通人群。点刺试验阳性和阴性的患者前庭症状无差异。然而,需要获取更大的样本量以使数据更可靠,并与对照组进行比较。

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