Keenan R J, List A, Kengsakul C
Department of Radiology, Auckland Hospital, New Zealand.
Australas Radiol. 1990 May;34(2):137-41. doi: 10.1111/j.1440-1673.1990.tb02829.x.
100 consecutive patients routinely referred for intravenous urography were examined using low doses of the low osmolar contrast medium Iohexol (Omnipaque 350mgl/ml). Their dosage schedule was based on the physiological parameters of age, sex, body weight and renal function. Comparison with a control group using standard contrast doses revealed a 42% reduction in contrast could be used, and still produce diagnostic studies. Nephrographic quality was reduced in the low dose group requiring technique modification, in particular a delayed film sequence. Further reductions in contrast use are envisaged in patients over the age of 40 years.
对100例常规转诊接受静脉肾盂造影的患者，使用低剂量的低渗性造影剂碘海醇（欧乃派克350mgl/ml）进行检查。他们的给药方案基于年龄、性别、体重和肾功能等生理参数。与使用标准造影剂剂量的对照组相比，结果显示造影剂用量可减少42%，且仍能进行诊断性检查。低剂量组的肾造影质量有所下降，需要改进技术，特别是采用延迟拍片序列。预计40岁以上的患者造影剂用量可进一步减少。
