Kowalczuk C I, Saunders R D
National Radiological Protection Board, Chilton, Didcot, Oxon, England.
Bioelectromagnetics. 1990;11(2):129-37. doi: 10.1002/bem.2250110204.
Male C3H/He mice were sham-exposed or exposed continuously for 2 weeks to a vertical, 50-Hz, electric field at 20 kV/m rms. Densities of currents induced in the testes are estimated to be near 100 microA/m2. After the exposure, each male was mated with two different female mice each week during a period of 8 weeks. By this schedule, female mice were impregnated with sperm that had been exposed to the electric field at different stages of the spermatogenic cycle. No significant differences as a function of exposure condition were observed in pregnancy rates or in survival of embryos before or after implantation. The absence of effects was not due to insensitivity of assays; other mice that were exposed to X-rays (dose to testes = 1.5 Gy) presented reliable evidence of mutagenesis.
雄性C3H/He小鼠接受假暴露或连续2周暴露于均方根值为20 kV/m的垂直50 Hz电场中。据估计，睾丸中感应电流的密度接近100微安/平方米。暴露后，在8周的时间里，每只雄性小鼠每周与两只不同的雌性小鼠交配。按照这个安排，雌性小鼠被注入了在生精周期不同阶段暴露于电场的精子。在怀孕率或植入前后胚胎的存活率方面，未观察到与暴露条件相关的显著差异。未出现影响并非由于检测方法不敏感；其他暴露于X射线（睾丸剂量 = 1.5 Gy）的小鼠呈现出可靠的诱变证据。
