Inserm, UMR, université de Nantes, l'institut du thorax, CHU de Nantes, France.
Arch Cardiovasc Dis. 2012 Feb;105(2):114-21. doi: 10.1016/j.acvd.2011.11.004. Epub 2012 Feb 9.
Progress in the medical treatment of patients with heart failure with systolic dysfunction, cardiac resynchronization therapy, internal cardiac defibrillators and multidisciplinary management programmes has resulted in dramatic improvements in survival and quality of life; however, this progress has led to an increase in the prevalence of advanced heart failure. In the context of organ shortage for cardiac transplantation, the technological developments in left ventricular assist devices, shown in recent positive clinical studies, provide real hope for patients with advanced heart failure. This article summarizes the most recent clinical studies concerning left ventricular assist devices and discusses for whom and when a left ventricular assist device should be proposed.
心力衰竭伴收缩功能障碍患者的医学治疗取得了进展，心脏再同步治疗、心脏内除颤器和多学科管理方案使患者的生存率和生活质量得到了显著提高；然而，这一进展导致了晚期心力衰竭的发病率增加。在心脏移植器官短缺的情况下，左心室辅助装置的技术发展在最近的阳性临床研究中得到了证实，为晚期心力衰竭患者带来了真正的希望。本文总结了关于左心室辅助装置的最新临床研究，并讨论了何时以及针对哪些患者应提出左心室辅助装置的建议。
