Department of Neurology, Ziekenhuis Oost-Limburg, Schiepse Bos, 6, 3600 Genk, Belgium.
Acta Neurol Belg. 2012 Mar;112(1):67-9. doi: 10.1007/s13760-012-0018-0. Epub 2012 Feb 3.
The diagnosis of transient headache with neurological deficits and CSF lymphocytosis (HaNDL) is essentially based on the clinical and CSF findings, and the absence of MRI abnormalities. We present a young man with the clinical characteristics of HaNDL, but also an area of diffusion restriction in the splenium of the corpus callosum (SCC). When considering the limited experience with this MRI technique in this disorder, we wonder if a normal MRI can be maintained as an indispensable criterion for diagnosis. Similar MRI abnormalities limited to the SCC have been found in mild forms of meningoencephalitis, but their origin remains obscure. In at least some cases not only a clinical, but also a radiological overlap could exist between both disorders.
具有神经功能缺损和脑脊液淋巴细胞增多的短暂性头痛（HaNDL）的诊断主要基于临床和脑脊液检查结果，并且没有 MRI 异常。我们报告了一位具有 HaNDL 临床特征的年轻男性，但胼胝体压部（SCC）也存在弥散受限区域。当考虑到这种 MRI 技术在这种疾病中的有限经验时，我们想知道是否可以将正常的 MRI 作为诊断的不可或缺标准。在脑膜脑炎的轻度形式中也发现了类似的仅限于 SCC 的 MRI 异常，但它们的起源仍然不清楚。在至少一些情况下，两种疾病之间不仅存在临床重叠，而且还存在放射学重叠。
