Cornick J L, Seahorn T L
Department of Large Animal Medicine and Surgery, Texas Veterinary Medical Center, College of Veterinary Medicine, Texas A&M University, College Station 77840.
J Am Vet Med Assoc. 1990 Oct 15;197(8):1054-9.
During a 3 1/2-year period, cardiac arrhythmias were identified in 6 of 67 horses diagnosed with duodenitis/proximal jejunitis (DPJ). Arrhythmias were detected by auscultation of irregular cardiac rhythm and subsequently were characterized by electrocardiographic evaluation. Arrhythmias included frequent second-degree atrioventricular block, ventricular ectopic depolarizations, and atrioventricular conduction disturbance. In 4 horses, arrhythmias resolved with recovery from the primary problem. One horse died suddenly 66 hours after admission, and another was euthanatized at 72 hours after admission. Clinical and laboratory data from horses with DPJ and cardiac arrhythmias (group 1) were compared with findings for horses with DPJ and without arrhythmias (group 2). Group-1 horses had significantly (P less than 0.05) higher serum bicarbonate concentration and serum creatine kinase activity. Normal sinus rhythm returned in all 4 group-1 horses that recovered from DPJ, suggesting a causal relationship between DPJ and the arrhythmias. Two group-1 horses were necropsied, and both had myocarditis. The cause of these lesions was not determined.
在3年半的时间里，67匹被诊断患有十二指肠炎/空肠近端炎（DPJ）的马中有6匹出现了心律失常。心律失常通过听诊不规则心律被发现，随后通过心电图评估进行特征描述。心律失常包括频发二度房室传导阻滞、室性异位去极化和房室传导障碍。4匹马的心律失常随着原发性问题的恢复而消失。一匹马在入院66小时后突然死亡，另一匹马在入院72小时后实施了安乐死。将患有DPJ和心律失常的马（第1组）的临床和实验室数据与患有DPJ但没有心律失常的马（第2组）的检查结果进行了比较。第1组马的血清碳酸氢盐浓度和血清肌酸激酶活性显著更高（P<0.05）。从DPJ中恢复的所有4匹第1组马均恢复了正常窦性心律，这表明DPJ与心律失常之间存在因果关系。对2匹第1组马进行了尸检，二者均患有心肌炎。这些病变的病因尚未确定。
