Johnston J K, Morris D D
Department of Clinical Studies, School of Veterinary Medicine, New Bolton Center, University of Pennsylvania, Kennett Square 19348.
J Am Vet Med Assoc. 1987 Oct 1;191(7):849-54.
Sixty-eight horses with colic caused by small intestinal disease were allotted into 2 groups of 34 on the basis of recorded findings during exploratory celiotomy, necropsy, or response to medical treatment alone. Signalment, history, physical examination findings, and laboratory findings were compared between the group of horses with small intestinal obstruction and the group with duodenitis/proximal jejunitis. A significantly greater proportion of horses with duodenitis/proximal jejunitis were older than 2 years old (P less than 0.05). Differences in sex or breed distribution, or in seasonality of the 2 disease syndromes were not observed. Horses with duodenitis/proximal jejunitis had significantly greater signs of depression than those with small intestinal obstruction (P less than 0.01), and horses with small intestinal obstruction had significantly greater signs of abdominal pain (P less than 0.05). The mean heart and respiratory rates were significantly lower (P less than 0.01) and the volume of nasogastric reflux was significantly greater (P less than 0.05) in the group of horses with duodenitis/proximal jejunitis. Sections of small intestine that were palpable per rectum were less distended and there were more auscultable borborygmi in horses with duodenitis/proximal jejunitis, compared with those with small intestinal obstruction (P less than 0.05 and P less than 0.01). The group of horses with duodenitis/proximal jejunitis had lower mean plasma potassium and higher mean plasma bicarbonate concentrations (P less than 0.05) than the group with small intestinal obstruction. The mean nucleated cell count and total protein concentration of peritoneal fluid specimens were significantly less in the group with duodenitis/proximal jejunitis (P less than 0.01); however, these values were greater than normal.(ABSTRACT TRUNCATED AT 250 WORDS)
68匹因小肠疾病引发腹痛的马匹，根据剖腹探查术、尸检记录结果或单纯药物治疗反应，被分为两组，每组34匹。对小肠梗阻组和十二指肠炎症/空肠近端炎症组的马匹进行了品种特征、病史、体格检查结果及实验室检查结果的比较。十二指肠炎症/空肠近端炎症组中2岁以上马匹的比例显著更高（P小于0.05）。未观察到两种疾病综合征在性别或品种分布以及季节性方面的差异。十二指肠炎症/空肠近端炎症组马匹的抑郁症状显著多于小肠梗阻组（P小于0.01），而小肠梗阻组马匹的腹痛症状显著更严重（P小于0.05）。十二指肠炎症/空肠近端炎症组马匹的平均心率和呼吸频率显著更低（P小于0.01），鼻胃反流液量显著更多（P小于0.05）。与小肠梗阻组相比，十二指肠炎症/空肠近端炎症组经直肠可触及的小肠段扩张程度更低，可闻及的肠鸣音更多（P小于0.05和P小于0.01）。十二指肠炎症/空肠近端炎症组马匹的平均血浆钾浓度更低，平均血浆碳酸氢盐浓度更高（P小于0.05）。十二指肠炎症/空肠近端炎症组腹膜液标本的平均有核细胞计数和总蛋白浓度显著更低（P小于0.01）；然而，这些值高于正常水平。（摘要截选至250词）
