White N A, Tyler D E, Blackwell R B, Allen D
J Am Vet Med Assoc. 1987 Feb 1;190(3):311-5.
Records of 20 horses with small intestinal disease causing acute colic and affecting the proximal portion of the small intestine were examined retrospectively. The disease was characterized by severe to moderate pain, which was replaced by depression, fever, gastric reflux, slight distention of the affected small intestine, leukocytosis, and high concentrations of total protein in the peritoneal fluid. Grossly, the affected intestines were hemorrhagic and had yellow discoloration. Histopathologic findings included submucosal edema, neutrophilic infiltration of the submucosal and laminal propria, and mucosal slough at the villous tips. Advanced lesions were characterized by mucosal sloughing with transmural edema, hemorrhage, fibrin deposition, and necrosis. No cause was determined. In 6 horses, bypass of most of the affected small intestine was helpful by alleviating the severe gastric reflux.
对20匹患有导致急性腹痛的小肠疾病且病变累及小肠近端的马匹记录进行了回顾性研究。该疾病的特征为严重至中度疼痛，随后出现精神沉郁、发热、胃反流、受累小肠轻度扩张、白细胞增多以及腹腔积液中总蛋白浓度升高。大体上，受累肠段呈出血性且有黄色变色。组织病理学发现包括黏膜下水肿、黏膜下层和固有层的中性粒细胞浸润以及绒毛尖端的黏膜脱落。进展期病变的特征为黏膜脱落伴透壁性水肿、出血、纤维蛋白沉积和坏死。病因未明确。在6匹马中，大部分受累小肠的旁路手术通过减轻严重的胃反流而起到了帮助作用。
