Ou Ming-Chiu, Hsu Tsung-Fu, Lai Andrew C, Lin Yu-Ting, Lin Chia-Ching
Department of Applied Cosmetology, Hungkuang University, Taichung, Taiwan.
J Obstet Gynaecol Res. 2012 May;38(5):817-22. doi: 10.1111/j.1447-0756.2011.01802.x. Epub 2012 Mar 22.
This study assessed the effectiveness of blended essential oils on menstrual cramps for outpatients with primary dysmenorrhea and explored the analgesic ingredients in the essential oils.
A randomized, double-blind clinical trial was conducted. Forty-eight outpatients were diagnosed with primary dysmenorrhea by a gynecologist and had 10-point numeric rating scales that were more than 5. The patients were randomly assigned to an essential oil group (n = 24) and a synthetic fragrance group (n = 24). Essential oils blended with lavender (Lavandula officinalis), clary sage (Salvia sclarea) and marjoram (Origanum majorana) in a 2:1:1 ratio was diluted in unscented cream at 3% concentration for the essential oil group. All outpatients used the cream daily to massage their lower abdomen from the end of the last menstruation continuing to the beginning of the next menstruation.
Both the numeric rating scale and the verbal rating scale significantly decreased (P < 0.001) after one menstrual cycle intervention in the two groups. The duration of pain was significantly reduced from 2.4 to 1.8 days after aromatherapy intervention in the essential oil group.
Aromatic oil massage provided relief for outpatients with primary dysmenorrhea and reduced the duration of menstrual pain in the essential oil group. The blended essential oils contain four key analgesic components that amount to as much as 79.29%; these analgesic constitutes are linalyl acetate, linalool, eucalyptol, and β-caryophyllene. This study suggests that this blended formula can serve as a reference for alternative and complementary medicine on primary dysmenorrhea.
本研究评估了混合精油对原发性痛经门诊患者月经痛的疗效，并探索了精油中的镇痛成分。
进行了一项随机、双盲临床试验。48名门诊患者经妇科医生诊断为原发性痛经，且数字评分量表得分为10分且大于5分。患者被随机分为精油组（n = 24）和合成香料组（n = 24）。精油组将薰衣草（Lavandula officinalis）、鼠尾草（Salvia sclarea）和马郁兰（Origanum majorana）按2:1:1的比例混合，以3%的浓度稀释于无香乳膏中。所有门诊患者从上次月经结束开始至下次月经开始每天使用该乳膏按摩下腹部。
两组在经过一个月经周期的干预后，数字评分量表和语言评分量表均显著降低（P < 0.001）。精油组在芳香疗法干预后疼痛持续时间从2.4天显著缩短至1.8天。
芳香油按摩为原发性痛经门诊患者提供了缓解，并缩短了精油组的月经疼痛持续时间。混合精油含有四种关键镇痛成分，含量高达79.29%；这些镇痛成分是乙酸芳樟酯、芳樟醇、桉叶素和β-石竹烯。本研究表明，这种混合配方可为原发性痛经的替代和补充医学提供参考。
