Department of Pediatrics, University Federico II, Naples, Italy.
J Pediatr Gastroenterol Nutr. 2012 Jul;55(1):72-5. doi: 10.1097/MPG.0b013e3182549c44.
The association between GERD and obesity has been frequently reported in adults. Data in children are scarce and inconclusive, evaluating only general obesity. Central adiposity has never been investigated in children as a possible risk factor for GERD. The aims of the present study were to evaluate the prevalence of gastroesophageal reflux disease (GERD) symptoms in overweight and obese children in comparison with a general normal-weight population and whether the GERD symptoms are associated with waist circumference (WC).
The study population consisted of 153 healthy children. A detailed clinical history and a physical examination were obtained from each patient. A questionnaire on reflux symptoms was completed by caregivers.
The reflux symptomatic score resulted significantly higher in obese than in normal-weight children and in children with WC >90th percentile compared with those with WC <75th percentile.
These preliminary data show that both total and abdominal obesity are risk factors for the development of GERD symptoms in children. The risk of GERD symptoms rises progressively with the increase in both body mass index and waist circumference, even in normal-weight children.
胃食管反流病(GERD)与肥胖的相关性在成人中经常被报道。儿童的数据则很少且不确定,仅评估了一般肥胖。儿童的中心性肥胖从未被作为 GERD 的一个可能危险因素进行过调查。本研究的目的是评估超重和肥胖儿童与一般正常体重儿童相比 GERD 症状的患病率,以及 GERD 症状是否与腰围(WC)相关。
研究人群由 153 名健康儿童组成。每位患者均接受详细的临床病史和体格检查。照顾者完成了一份关于反流症状的问卷。
肥胖儿童的反流症状评分明显高于正常体重儿童,WC 超过第 90 百分位数的儿童高于 WC 低于第 75 百分位数的儿童。
这些初步数据表明,全身肥胖和腹部肥胖都是儿童 GERD 症状发展的危险因素。即使在正常体重的儿童中,随着体重指数和腰围的增加,GERD 症状的风险也会逐渐增加。