Lee Chong-Suh, Jung Chul-Hee
Department of Orthopaedic Surgery, Spine Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Asian Spine J. 2012 Mar;6(1):71-87. doi: 10.4184/asj.2012.6.1.71. Epub 2012 Mar 9.
In accordance with extending survival periods of cancer patients, number of consecutively developing metastatic spinal tumor is also increasing. There have been improvements in the treatment results of metastatic spine tumor by virtue of the developments in diagnostic radiology, chemotherapy, adjuvant treatment, operative device and technique, discrete preoperative plan, and standardized operation. Accordingly, surgical indication has also increased. Clinically, in case of metastatic spine tumor, treatment of tumor itself should be focused on pain relief, preservation of neurologic function, prevention of pathologic fracture, prevention of pathologic fracture, and correction of spinal instability for improving quality of life, rather than for extension of survival. Additionally, etiology of spinal tumor, correct diagnosis and subsequent treatment principles should be thoroughly understood before establishing treatment plans for effective treatments.
随着癌症患者生存期的延长,连续发生的转移性脊柱肿瘤数量也在增加。由于诊断放射学、化疗、辅助治疗、手术器械和技术、精确的术前规划以及标准化手术的发展,转移性脊柱肿瘤的治疗效果有所改善。相应地,手术适应证也有所增加。临床上,对于转移性脊柱肿瘤,治疗肿瘤本身应侧重于缓解疼痛、保留神经功能、预防病理性骨折、纠正脊柱不稳以提高生活质量,而非延长生存期。此外,在制定有效治疗方案之前,应充分了解脊柱肿瘤的病因、正确诊断及后续治疗原则。